Indian Journal of Forensic Medicine & Toxicology

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Intravascular Hemolysis after Aluminum Phosphide Poisoning


Affiliations
1 Forensic Medicine Dept., Tehran University of Medical Sciences, Baharloo Hospital, Tehran, Iran, Islamic Republic of
2 Kurdistan Digestive and Hepatic Diseases Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran, Islamic Republic of
     

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Background: hemolysis is a rare finding in patients with Aluminum phosphide (AlP) poisoning. In this report a patient with the AlP poisoning and intravascular hemolysis will be presented.

Case Report: The patient was a 25 years old man who ingested three tablets (9gr) of AlP for suicide attempt one hour before admission to poisoning emergency ward of Baharloo hospital in Tehran. He had nausea, vomiting, heartburn, and mild metabolic acidosis on the arrival to the hospital. The patient had no fever, loss of consciousness and respiratory distress. History of specific disease and concomitant use of other drugs was not mentioned. Supportive care was done for the patient. He was icteric and his serum bilirubin was increased and hemoglobin was decreased 24 hour after admission during hospitalization. Laboratory tests were negative for hepatitis and liver, gall bladder and bile duct ultrasound was normal. G6PD (glucose 6 phosphate dehydrogenase) deficiency was confirmed. The patient was discharged with the good condition after a week.

Conclusion: Due to lack of other drug use and the underlying causes for hemolysis in this case, it seems ALP should be added to the etiologies of hemolysis in patients with glucose 6-phosphate dehydrogenase deficiency.


Keywords

Aluminum phosphide, Poisoning, Hemolysis, G6PD deficiency
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  • Intravascular Hemolysis after Aluminum Phosphide Poisoning

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Authors

M. Arefi
Forensic Medicine Dept., Tehran University of Medical Sciences, Baharloo Hospital, Tehran, Iran, Islamic Republic of
V. Allahyar Parsa
Forensic Medicine Dept., Tehran University of Medical Sciences, Baharloo Hospital, Tehran, Iran, Islamic Republic of
V. Yousefinejad
Kurdistan Digestive and Hepatic Diseases Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran, Islamic Republic of
N. Darvishi
Kurdistan Digestive and Hepatic Diseases Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran, Islamic Republic of

Abstract


Background: hemolysis is a rare finding in patients with Aluminum phosphide (AlP) poisoning. In this report a patient with the AlP poisoning and intravascular hemolysis will be presented.

Case Report: The patient was a 25 years old man who ingested three tablets (9gr) of AlP for suicide attempt one hour before admission to poisoning emergency ward of Baharloo hospital in Tehran. He had nausea, vomiting, heartburn, and mild metabolic acidosis on the arrival to the hospital. The patient had no fever, loss of consciousness and respiratory distress. History of specific disease and concomitant use of other drugs was not mentioned. Supportive care was done for the patient. He was icteric and his serum bilirubin was increased and hemoglobin was decreased 24 hour after admission during hospitalization. Laboratory tests were negative for hepatitis and liver, gall bladder and bile duct ultrasound was normal. G6PD (glucose 6 phosphate dehydrogenase) deficiency was confirmed. The patient was discharged with the good condition after a week.

Conclusion: Due to lack of other drug use and the underlying causes for hemolysis in this case, it seems ALP should be added to the etiologies of hemolysis in patients with glucose 6-phosphate dehydrogenase deficiency.


Keywords


Aluminum phosphide, Poisoning, Hemolysis, G6PD deficiency

References