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Hormonal and Immunological Study in Serum of Pregnant albino rats Treated with Nickel Oxide Nanoparticles


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1 Babylon University/College of Science, Iraq
     

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The present study was aimed to elucidate the effect of Nickel oxide nanoparticle (100mg /kg b.wt) on some parameters in pregnant Albino rats which including serum reproductive hormonal level, Leutinlizing Hormone (LH), Follicle stimulating Hormone ( FSH) and Testosterone (Test), and some Immunoglobulin levels (IgA, IgG, IgM) for different period of pregnancy ( 12 and 14 days). The hormonal results showed significant (P≤0.05) increased of treatment groups as compared with control groups. Immunological results showed significant decreases in treated groups as compared with control groups, It could be concluded that increasing concentrations of NIO- NPs and durations of exposure leads to negative effects on the pregnant albino rat.

Keywords

NIO, Nanoparticles, Albino Rats, Hormones, Immunoglobulin.
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  • Hormonal and Immunological Study in Serum of Pregnant albino rats Treated with Nickel Oxide Nanoparticles

Abstract Views: 99  |  PDF Views: 0

Authors

Haneen M. Alsoltane
Babylon University/College of Science, Iraq
Amel A. Altaee
Babylon University/College of Science, Iraq

Abstract


The present study was aimed to elucidate the effect of Nickel oxide nanoparticle (100mg /kg b.wt) on some parameters in pregnant Albino rats which including serum reproductive hormonal level, Leutinlizing Hormone (LH), Follicle stimulating Hormone ( FSH) and Testosterone (Test), and some Immunoglobulin levels (IgA, IgG, IgM) for different period of pregnancy ( 12 and 14 days). The hormonal results showed significant (P≤0.05) increased of treatment groups as compared with control groups. Immunological results showed significant decreases in treated groups as compared with control groups, It could be concluded that increasing concentrations of NIO- NPs and durations of exposure leads to negative effects on the pregnant albino rat.

Keywords


NIO, Nanoparticles, Albino Rats, Hormones, Immunoglobulin.



DOI: https://doi.org/10.37506/v14%2Fi1%2F2020%2Fijfmt%2F193063