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Dimri, Sanjeev
- A Study of Inducible Clindamycin Resistance in Staphylococci in a Tertiary Care Hospital in Western Uttar Pradesh
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Authors
Affiliations
1 Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, (UP), IN
1 Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, (UP), IN
Source
International Journal of Contemporary Medicine, Vol 1, No 2 (2013), Pagination: 7-10Abstract
Aim: The aim of this study was to determine inducible clindamycin resistance in erythromycinresistant, clindamycin-sensitive staphylococcal strains isolated from clinical specimens. Material and Method: A total of 108 erythromycin-resistant, clindamycin-sensitive staphylococcal isolates from various clinical specimens were tested using D-test according to CLSI guidelines. Result: A total of 23 (21.3%) staphylococcal isolates were found to be D-test positive and demonstrated inducible clindamycin resistance (iMLSB phenotype). MRSA isolates showed highest percentage (25.8%) of inducible clindamycin resistant phenotypes. Conclusion: Inducible clindamycin resistance should be checked in staphylococcal isolates before administering clindamycin therapy in staphylococcal infections as it can lead to clinical failure.Keywords
D-test, MRSA, iMLSB Phenotype , Clindamycin, erm Methylase.
References
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- Isolated Thrombocytopenia in Pulmonary Tuberculosis: A Case Report and Review
Abstract Views :274 |
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Authors
Affiliations
1 Columbia Asia Hospital, Ghaziabad, U.P, IN
2 Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, U.P, IN
1 Columbia Asia Hospital, Ghaziabad, U.P, IN
2 Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, U.P, IN
Source
International Journal of Contemporary Medicine, Vol 1, No 2 (2013), Pagination: 84-86Abstract
Introduction: Isolated thrombocytopenia in association with childhood tuberculosis is a rare event and occasional reports are described in pediatric literature. We describe a case of isolated thrombocytopenia associated with active pulmonary tuberculosis in a three year old girl with no history of intake of anti tubercular drugs.
Case report: A three year old girl presented with low grade fever, decreased appetite, dry cough for six weeks and generalized cutaneous petechial rash for one day with no history of bleeding sites, hematuria or malena. Hematologic investigations, mantoux test and chest X-ray were advised.
Findings: Hematologic investigations revealed that TLC and DLC were within normal limits while platelets could not be demonstrated on peripheral blood smear.ESR was raised and mantoux test was positive. Chest X-ray revealed bilateral miliary shadows.
Treatment: The patient was treated successfully with anti tubercular drugs and a short steroid therapy.
Review: Above case was discussed in light of literature available in the matter.
Keywords
Thrombocytopenia, Peticheal Rash, Pulmonary Tuberculosis, ATT.References
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