Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Deshmukh, Geeta
- Seroprevalence of HIV Antibodies in Healthy Blood Donors in a University Blood Bank of Western U.P. and National Capital Region, India - A 4 Year Study
Abstract Views :300 |
PDF Views:0
Authors
Affiliations
1 Pathology, School of Medical Sciences & Research, Sharda Hospital Greater Noida, U.P., IN
2 Pathology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida, U.P, IN
3 Consultant Pediatrician in Ghaziabad & Greater Noida, IN
1 Pathology, School of Medical Sciences & Research, Sharda Hospital Greater Noida, U.P., IN
2 Pathology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida, U.P, IN
3 Consultant Pediatrician in Ghaziabad & Greater Noida, IN
Source
International Journal of Contemporary Medicine, Vol 1, No 1 (2013), Pagination: 79-83Abstract
The acute medical services cannot exist without blood transfusion - life savers in many situations. Usually, giving blood is generous. Sometimes, however, it is lethal. In countries where blood donors get paid by the pint, drug addicts, street dwellers & others who have little to sell except their bodies flock to for - profit blood centers. Many of these people carry AIDS virus. If one blood bank tests for AIDS antibodies & defers the HIV positive volunteers away - forget about treating them - those poor and desperate enough can often find another ,less scrupulous blood bank or a hospital that doesn't do the testing properly. Such hospitals continue to flourish and nobody knows from whose veins the blood is flowing from. The inevitable result is a frightening rate of contamination. Infection through blood is a major issue in all countries but practically in those with economic constraints with limited safety. The present study was conducted to find out the seroprevalence of HIV antibodies in 6000 donors in a tertiary medical centre. The screening was done by ELISA third generation microelisa kit. Seroprevalence of anti - HIV in 6000 donors was 0.1833% Males show higher incidence and no female donor was found to be HIV seropositive in this study. Also, no voluntary donor was found to be positive for HIV. Blood group A negative showed higher positivity (1.075%) followed by blood group B positive (0.2545%) Age group 41-50 years showed highest positivity (0.3048%) followed by 21-30 yrs (0.2087%).Keywords
Human Immunodeficiency Virus, Seroprevalence, Blood Donors, ELISA.
References
- Arora D, Arora B, Khetrapal A. Seroprevalence of HIV,HBV,HCV and syphilis in blood donors in south Haryana. Indian J pathol microbial. 2010;53:308-309.doi:10.4103/0377-4929.64295.
- Rao P, Annapurna K.HIV status of blood donors and patients admitted in KEM hospital, Pune.Ind J heat blood transf.1994;12:174-176
- Dolly R, Annie S, Thaiyanayaki P, George PB, Jacob TH. Increasing prevalence of HIV antibody among blood donors monitored over 9 years in blood bank. Indian J med Res.1998; 108:42 -44.
- Singh K, Bhat S, Shasry S. Trend in seroprevalence of hepatitis B virus infection among blood donors of coastal Karnataka, India. J infect Dev Ctries.2009; 3:376 -379.
- Pahuja S, Sharma M, Baitha B, Jain M. Prevalence and trends of markers of hepatitis C virus, hepatitis B virus and immunodeficiency virus in Delhi blood donors. A hospital based study. Jpn J Inf Dis.2007; 60:389-391.
- Singh B, Verma M, Kotru M, Verma K, Batra M. Prevalence of HIV & VDRL seropositivity in blood donors of Delhi. Indian J Med Res.2005; 122:234 -236.
- Kakkar N, Kaur R, Dhanoa J. voluntary donors – need for a second look. Indian J pathol Microbiol.2004; 47:381-383.
- Makroo RN, Sahil P, Vashist RP, Lal S. Trends of HIV infection in blood donors of Delhi. Indian J Pathol Microbiol.1996; 39:139 -142.
- Chandra T, Kumar A, Gupta A. Prevalence of transfusion transmitted infections in blood donors: an Indian experience. Trop. Doct. 2009;39:152-154.doi:10.1258/td.2008.080330.
- Joshi SR. Seropositivity status for HIV infection among voluntary and replacement blood donors in the city of Surat from western India. Indian J Hemat Blood Transf.1988; 16:20 -21.
- Sonwane BR, Birare SD, Kulkarni PV. Prevalence of seroreactivity among blood donors in rural population. Indian Med Sci.2003; 57:405-407.
- Maity S, Nandi S, Biswas S, Saha MK. Human immunodeficiency virus seroprevalence among patients attending a sexually transmitted disease clinic in west Bengal, India.Jpn J Infect Dis.2012;65(5):424-6
- Pando MA, Coloccini RS, Schvachsa N,Pippo M, Alfie LG, Marone R, Gomez – Carrillo M, Avila MM, Salomon H. Improved strategies for HIV diagnosis among men who have sex with men(MSM) in Buneos Aires, Argentina, a population with a high prevalence and incidence of HIV infection.HIV Med.2012 Oct;13(9):564- 7.doi:10.1111/j.1468-1293.2012.01011.x.Epub 2012 Mar 21.
- Day S, Ward H, Perrotta L. Prostitution and risk of HIV: male partners of female prostitutes.
- Bone Marrow Aspiration and Bone Marrow Biopsy in Hematological Malignancies - A 10 Year Clinicopathological Study
Abstract Views :291 |
PDF Views:0
Authors
Affiliations
1 Department of Pathology, Mayo Institute of Medical Sciences, Gadia, Barabanki, Lucknow, Uttar Pradesh, IN
2 Department of Medicine, School of Medical Science and Research, Sharda Hospital, Greater Noida, Uttar Pradesh, IN
3 Department of Pathology, School of Medical Science and Research, Sharda Hospital, Greater Noida, Uttar Pradesh, IN
4 Department of Pathology, Santosh Medical College, Ghaziabad, Uttar Pradesh, IN
1 Department of Pathology, Mayo Institute of Medical Sciences, Gadia, Barabanki, Lucknow, Uttar Pradesh, IN
2 Department of Medicine, School of Medical Science and Research, Sharda Hospital, Greater Noida, Uttar Pradesh, IN
3 Department of Pathology, School of Medical Science and Research, Sharda Hospital, Greater Noida, Uttar Pradesh, IN
4 Department of Pathology, Santosh Medical College, Ghaziabad, Uttar Pradesh, IN
Source
International Journal of Contemporary Medicine, Vol 1, No 1 (2013), Pagination: 95-99Abstract
Introduction: Hematological malignancies may derive from either of the two major blood cell lineages- Myeloid and lymphoid cell lines. Lymphoma, lymphocytic leukemias and myeloma are from the lymphoid line, while acute and chronic myelogenous leukemia, myelodysplastic syndromes and myeloproliferative diseases are myeloid in origin.
Objectives : The present study (2002 - 2012) has been aimed to report our bone marrow aspiration and biopsy examination experience with one hundred seven (107) patients of hematological malignancies from North India. and compare the results of bone marrow aspirations with bone marrow biopsy.
Material and Methods: In our study we have included cases of hematological malignancies (Leukemia, Malignant Lymphoma and Multiple Myeloma). In each case serial bone marrow aspiration and biopsy were done before and after chemotherapy and radiotherapy. Aspirate particles, smears, touch imprints of the biopsy core and paraffin sections of the biopsy core were routinely examined.
Results: Out of these one hundred seven (107) cases of hematological malignancies, non-Hodgkin's lymphoma (NHL) were maximum thirty cases (28.03%), followed by chronic myeloid leukemia (CML) twenty cases (18.69%), acute lymphoblastic leukemia (ALL) fifteen cases (14.01%), acute myeloid leukemia (AML) twelve cases (11.21%), multiple myeloma (MM) eleven cases (10.28%), chronic lymphocytic leukemia (CLL) ten cases (09.34%), Hodgkin's lymphoma (HL) eight cases (07.47%) and hairy cell leukemia (HCL) one case (0.93%).
Conclusion: Hematological malignancies were more prevalent in males and more common in first and third decades of life followed by fifth decade In this study bone marrow aspiration was found adequate in hematological malignancies especially in leukemia. Trephine biopsy is essential for diagnosis, when a dry tap or bloody tap occurs as a result of fibrotic or very densely cellular bone marrow. There is virtually no contraindication to aspiration and needle biopsy of the bone marrow. In malignant lymphomas, which are infiltrating to bone marrow, bone marrow biopsy (BMB) was found superior to bone marrow aspiration (BMA) as well as bone marrow involvement is a less favorable prognostic sign than the patients without bone marrow involvement.
Keywords
Bone Marrow, Hematological Malignancies.References
- Anna Carter, Irit Hocherman, Shai linn et al (1987): Prognostic significance of plasma cell morphology in multiple myeloma. Cancer (60):1060 – 1065.
- Barbara J. Bain, David M. Clark and Irn A. Lampert (1992): Bone marrow pathology. Blackwell scientific publications. Oxford.
- Burkhardt R., Frisch B., and Bartl R. (1982): Bone marrow biopsy in hematological disorders. J. Clin. Pathol. (35): 257 – 284.
- Clain A. et al (1965): Secondary malignant disease of bone. Br. J. Cancer (19): 15 – 29.
- Islam A., Bertha Frisch and Handerson E. S. (1989): Laboratory techniques: Plastic embedded core biopsy: A complimentary approach to bone marrow aspiration for diagnosing acute myeloid leukemia. J. Clin. Pathol. (42): 300 – 306.
- James E. Bearden, Gary A. Ratkin and Charles A. Coltman (1974): Comparison of diagnostic value of bone marrow biopsy and bone marrow aspiration in neoplastic diseases. J. Clin. Pathol. (27): 738 – 740.
- Michael A. Simon and Eugene J. Bartucci (1986): The search for the primary tumor in patients with skeletal metastasis of unknown origin. Cancer (58): 1088 – 1095.
- Robert W. Mckenna and Jose A. Hernandez (1988): Bone marrow in malignant lymphoma. Hematology/Oncology clinics in North America. 2 (4): 617 – 635.
- Stephen E. Jones, Saul A. Rosenberg and Henry S. Kaplan (1972): Non Hodgkin’s lymphoma. 1- Bone marrow involvement. Cancer. (5): 954 - 960.
- Wolf C. De Peeters (1991): Bone marrow trephine interpretation: Diagnostic utility and potential pitfalls. Histipathology 18: 489 – 483.
- Role of Bone Marrow Study in Malignant Disorders: A Clinicopathological Study of 185 Patients
Abstract Views :288 |
PDF Views:2
Authors
Affiliations
1 Department of Pathology, Mayo institute of medical sciences, Gadia, Barabanki, Lucknow, Uttar Pradesh, IN
2 Department of Medicine, School of Medical Science and Research, Greater Noida, Uttar Pradesh, IN
3 Department of Pathology, Dr. B. R. Sur Homeopathic Medical College and Hospital and Research center, New Delhi, IN
4 Department of Pathology, School of Medical Science and Research, Greater Noida, Uttar Pradesh, IN
5 Santosh Medical College, Ghaziabad, Uttar Pradesh, IN
1 Department of Pathology, Mayo institute of medical sciences, Gadia, Barabanki, Lucknow, Uttar Pradesh, IN
2 Department of Medicine, School of Medical Science and Research, Greater Noida, Uttar Pradesh, IN
3 Department of Pathology, Dr. B. R. Sur Homeopathic Medical College and Hospital and Research center, New Delhi, IN
4 Department of Pathology, School of Medical Science and Research, Greater Noida, Uttar Pradesh, IN
5 Santosh Medical College, Ghaziabad, Uttar Pradesh, IN
Source
International Journal of Contemporary Medicine, Vol 1, No 2 (2013), Pagination: 36-40Abstract
Introduction: Bone marrow is a reservoir of stem cells and is the site of origin of numerous primary hematological malignancies and is commonly infiltrated by malignant cells in non-hematological malignancies in advanced stages. Objectives: The present study (2002 - 2012) has been aimed to report our experience with one hundred eighty five (185) patients from North India. A comparative study of bone marrow aspiration (BMA) and bone marrow biopsy (BMB) was done simultaneously, where the clinical history was correlated before and after chemotherapy and radiotherapy. Material and Method: In our study we have included cases of malignant disorders (hematological malignancies and non-hematological malignancies). In each case bone marrow aspiration and biopsy were done before and after chemotherapy and radiotherapy. Aspirate particles, smears, touch imprints of the biopsy core and paraffin sections of the biopsy core were routinely examined. Results: In our study we have included cases of hematological malignancies (Leukemia, Multiple Myeloma and Malignant Lymphoma) and non-hematological malignancies (Carcinoma of Breast, Prostate, Lung, Kidney, Urinary bladder, GIT, Thyroid, Round cell tumors and Indeterminate tumors). In hematological malignancies, non-Hodgkin's lymphomas (NHL) were maximum thirty cases (28.03%) and hairy cell leukemia (HCL) one case (0.93%). In non-hematological malignancies or primary tumors, there were maximum cases of breast carcinoma, twenty four cases (30.76%) and minimum two cases of thyroid carcinoma (02.56%). Conclusion: Malignant disorders were more prevalent in males and were seen in all the age groups. In this study bone marrow aspiration was found adequate in hematological malignancies especially in leukemia. Bone marrow biopsy found to be more informative in lymphoma and Metastatic tumors Bone marrow involvement indicated poor prognosis in metastatic tumors except in seven cases (18.42%) of malignant lymphoma. There was no complication of the procedure even in cases of thrombocytopenia.Keywords
Bone Marrow, Hematological Malignancies, Non-Hematological MalignanciesReferences
- Barbara J. Bain, David M. Clark and Irn A. Lampert (1992): Bone marrow pathology. Blackwell scientific publications. Oxford.
- Clain A. et al (1965): Secondary malignant disease of bone. Br. J. Cancer (19): 15 – 29.
- Coleman RE, Smith P. and Rubens RD (1998): Clinical course and prognostic factors following bone recurrence from breast cancer. Br. J. of Cancer. 77 (2): 336 – 340.
- Gupta R., Parikh PM and Advani SH et al (1989): Hodgkin’s disease with bone marrow involvement. Indian J. Cancer. (26): 58 – 66.
- James E. Bearden, Gary A. Ratkin and Charles A. Coltman (1974): Comparison of diagnostic value of bone marrow biopsy and bone marrow aspiration in neoplastic diseases. J. Clin. Pathol. (27): 738 – 740.
- James N. Ingle, Douglass C. Tormey, Joan M. Bull and Richard M. Simon (1977): Bone marrow involvement in breast cancer. Effect on response and tolerance to combination chemotherapy. Cancer. (39): 104 – 111.
- Jerry Z. Finklestein, Henry Ekert et al (1970): Bone marrow metastasis in children with solid tumors. Amer. J. Dis. Child. (119): 49 – 52.
- Kjurkchiev G. and Valkov I (1998): Role of touch imprints and core biopsy for detection of tumor metastasis in bone marrow. Diag-Cytopathol. 18 (5): 323 – 324.
- Michael A. Simon and Eugene J. Bartucci (1986): The search for the primary tumor in patients with skeletal metastasis of unknown origin. Cancer (58): 1088 – 1095.
- Richard A. Savage, George C. Hoffman and Keren Shaker R.N. (1978): Diagnostic problems involved in detection of metastatic neoplasm of bone marrow aspirates compared with needle biopsy. American J. Clin. Pathol. (70): 623 – 627.
- Robert W. Mckenna and Jose A. Hernandez (1988): Bone marrow in malignant lymphoma. Hematology/Oncology clinics in North America. 2 (4): 617 – 635.
- Stephen E. Jones, Saul A. Rosenberg and Henry S. Kaplan (1972): Non-Hodgkin’s lymphoma. 1- Bone marrow involvement. Cancer. (5): 954 - 960.
- Wolf C. De Peeters (1991): Bone marrow trephine interpretation: Diagnostic utility and potential pitfalls. Histipathology 18: 489 – 483.