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Antimicrobial Effects of Topical Skin Cream Containing Natural Oil Mixtures against Staphylococcus pseudintermedius and Malassezia pachydermatis


Affiliations
1 College of Veterinary Medicine, Konkuk University, Seoul, Korea, Republic of
 

The objective of this study was to evaluate the in vitro efficacy of a topical skin cream containing a mixture of emu oil, jojoba oil, avocado oil, and tea tree oil against the canine skin pathogens Staphylococcus pseudintermedius and Malassezia pachydermatis. Three S. pseudintermedius isolates from dogs and a type strain of M. pachydermatis were used. Based on the standards of the Clinical and Laboratory Standards Institute, the minimal inhibitory concentration (MIC) and the minimal bactericidal/fungicidal concentration (MBC/MFC) were determined. In addition, microbial inactivation time was determined for both pathogens. The MICs against S. pseudintermedius and M. pachydermatis were 0.23% and 0.63%, while the MBC/MFCs were 7.5% and 5%, respectively. In assessments of the microbial inactivation time, after 12 h of incubation with the cream, the growth of both pathogens was completely inhibited. These results suggest that the skin cream tested here can be used as a substitute for generally used antibiotic/antifungal agents.

Keywords

Natural Oil, Staphylococcus pseudintermedius, Malassezia pachydermatis, Antimicrobial Effect.
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  • Antimicrobial Effects of Topical Skin Cream Containing Natural Oil Mixtures against Staphylococcus pseudintermedius and Malassezia pachydermatis

Abstract Views: 171  |  PDF Views: 61

Authors

J. I. Han
College of Veterinary Medicine, Konkuk University, Seoul, Korea, Republic of
S. J. Park
College of Veterinary Medicine, Konkuk University, Seoul, Korea, Republic of
S. G. Kim
College of Veterinary Medicine, Konkuk University, Seoul, Korea, Republic of
H. M. Park
College of Veterinary Medicine, Konkuk University, Seoul, Korea, Republic of

Abstract


The objective of this study was to evaluate the in vitro efficacy of a topical skin cream containing a mixture of emu oil, jojoba oil, avocado oil, and tea tree oil against the canine skin pathogens Staphylococcus pseudintermedius and Malassezia pachydermatis. Three S. pseudintermedius isolates from dogs and a type strain of M. pachydermatis were used. Based on the standards of the Clinical and Laboratory Standards Institute, the minimal inhibitory concentration (MIC) and the minimal bactericidal/fungicidal concentration (MBC/MFC) were determined. In addition, microbial inactivation time was determined for both pathogens. The MICs against S. pseudintermedius and M. pachydermatis were 0.23% and 0.63%, while the MBC/MFCs were 7.5% and 5%, respectively. In assessments of the microbial inactivation time, after 12 h of incubation with the cream, the growth of both pathogens was completely inhibited. These results suggest that the skin cream tested here can be used as a substitute for generally used antibiotic/antifungal agents.

Keywords


Natural Oil, Staphylococcus pseudintermedius, Malassezia pachydermatis, Antimicrobial Effect.