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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, A.P, IN
2 Department of Pharmaceutical Chemistry, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, A.P, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 561-564
Abstract
The Present work describes a simple reverse phase HPLC method for the estimation of Domperidone in bulk and pharmaceutical formulations. The estimation was carried out on Gemini, Phenomonex, C-18 (250×4.6 mm, 5 μ) column using a mobile phase consisting of potassium dihydrogen phosphate buffer-Acetonitrile-Methanol (40:30:30). The eluent was monitored at 288 nm. The results have been validated statistically and recovery studies confirmed the accuracy of proposed method.
Keywords
HPLC Estimation, Validation, Domperidone and Pharmaceutical Formulation.
