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Salivary and Serum Glucose in relation to HbA1c Levels in Type 2 Diabetes Mellitus


Affiliations
1 Department of Biochemistry, Institute of Technology and Science - Centre for Dental Study and Research (ITS-CDSR), Ghaziabad, Uttar Pradesh, India
2 Department of Chemistry, Magadh University, Bodh Gaya, India
 

Diabetes Mellitus (DM) regularly requires blood investigation. Investigation which can efficiently measure the common parameters without painful collection procedure can be beneficial for the patients. The study aimed at measuring and correlating salivary and serum glucose along with serum HbA1C in patients of type 2 DM. The study was an observational case control study carried over a period of one year and four months. It included 42 type 2 DM patients as cases and 41 non diabetic patients as controls, from 35 to 70 years of age. Blood and saliva samples were collected. Serum and salivary glucose with serum HbA1C levels were measured and analysed using SPSS version 16. 55% of study subjects were < 45 years. M: F ratio was 3:2. The mean FBS, mean salivary glucose and HbA1C in type 2DM was 155.8 mg/dl, 20.4 mg/dl and 8.35 where as in control group they were 88.9 mg/dl, 9.35 mg/dl and 5.5 respectively. The FBS and the salivary glucose correlated significantly (p<0.001) and HbA1c levels had strong positive linear correlation to FBS and salivary glucose. Saliva is an effective medium for regular assessment of sugar level in DM. Key words: Saliva; HbA1c; blood sugar; diabetes mellitus.

Keywords

Saliva, Hba1c, Blood Sugar, Diabetes Mellitus.
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  • Salivary and Serum Glucose in relation to HbA1c Levels in Type 2 Diabetes Mellitus

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Authors

Dipti Soni Jaipuriar
Department of Biochemistry, Institute of Technology and Science - Centre for Dental Study and Research (ITS-CDSR), Ghaziabad, Uttar Pradesh, India
Arun Kumar Singh
Department of Chemistry, Magadh University, Bodh Gaya, India
Shivadhar Sharma
Department of Chemistry, Magadh University, Bodh Gaya, India

Abstract


Diabetes Mellitus (DM) regularly requires blood investigation. Investigation which can efficiently measure the common parameters without painful collection procedure can be beneficial for the patients. The study aimed at measuring and correlating salivary and serum glucose along with serum HbA1C in patients of type 2 DM. The study was an observational case control study carried over a period of one year and four months. It included 42 type 2 DM patients as cases and 41 non diabetic patients as controls, from 35 to 70 years of age. Blood and saliva samples were collected. Serum and salivary glucose with serum HbA1C levels were measured and analysed using SPSS version 16. 55% of study subjects were < 45 years. M: F ratio was 3:2. The mean FBS, mean salivary glucose and HbA1C in type 2DM was 155.8 mg/dl, 20.4 mg/dl and 8.35 where as in control group they were 88.9 mg/dl, 9.35 mg/dl and 5.5 respectively. The FBS and the salivary glucose correlated significantly (p<0.001) and HbA1c levels had strong positive linear correlation to FBS and salivary glucose. Saliva is an effective medium for regular assessment of sugar level in DM. Key words: Saliva; HbA1c; blood sugar; diabetes mellitus.

Keywords


Saliva, Hba1c, Blood Sugar, Diabetes Mellitus.