SMU Medical Journal

The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


Aloe vera product is well known for medicinal, cosmetic properties, and polymer for pharmaceutical industry. Aloe vera gel may be employed to effectively deliver poorly absorbable drugs through the oral route of drug administration. Ranitidine hydrochloride is a drug of choice in the treatment of ulcer. The drug has a short biological half-life of approximately 2-3 hours, thus a sustained release dosage form of ranitidine HCl is desirable. The aim of this study was to compare Aloe vera gel and Aloe vera powder as polymer mucoadhesive. The obtained results indicated that aloe vera powder has physical properties better than aloe vera gel. Drying process of aloe vera powder is important to improve their stability which performed by less of moisture content, increase of flow rate, swelling index, in vitro mucoadhesive, and dissolution. Aloe vera powder is a suitable polymer for local delivery in the gastrointestinal tract.

Keywords

Aloe Vera, Microgranules, Ranitidine HCl, Mucoadhesive Polymer, Gastrointestinal Tract.
User
Notifications
Font Size