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Production and Management of Specific Pathogen Free and Gnobiotic Animals
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Specific pathogen free animals are those animals which are free from a group of particular pathogen but these animals are not necessarily free from other organism, which are not specified, in the conducted experiment. Gnotobiotic: A word derived from the Greek "gnotos" and "biota" meaning known flora and fauna. An animal stock or strain derived by aseptic cesarean section (or sterile hatching of eggs) which are reared and continuously maintained with germfree techniques. According to International Committee on Laboratory Animals (ICLA) "Specific Pathogen Free (SPF) animals, which are free of specified micro-organism and parasites but not necessarily free of on the ones which are not specified." Synonyms of SPF animals are-Disease free animals, healthy animals, pathogen free animals, clean animals, caesarian derived animals.
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