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Mohite, S. K.
- Formulation and Optimization of Dermatological Dosage form for Comparative in-vitro Evaluation of Semisolid Bases
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Authors
Affiliations
1 Rajarambapu College of Pharmacy, Kasegaon, Tal- Walwa, Dist-Sangli, IN
1 Rajarambapu College of Pharmacy, Kasegaon, Tal- Walwa, Dist-Sangli, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 7, No 2 (2016), Pagination: 46-54Abstract
The aim of this study was to improve the permeation of Diclofenac Sodium. Permeation studies were carried out in - vitro using cellophane membrane. Topical formulations of diclofenac sodium were prepared by using various polymers. Gel, cream and ointment of the drug were prepared with polymers and the formulations were subjected for evaluation. Gel formulations were containing carbopol 940, triethanolamine, and preservatives. Cream was formulated by using stearic acid, glycerin, lanolin and preservatives. Ointment was also formulated by using the ingredients cetostearyl alcohol, hard paraffin, white soft paraffin and wool fat. In-vitro permeation studies by using cellophane membrane in diffusion cell revealed better permeation characteristics of diclofenac sodium. These types of topical dosage forms could give sustained delivery of drug on to the skin, so they are interesting promises to improve skin absorption of non steroidal anti-inflammatory drugs and to prevent side effects associated. The Topical formulations are excellent in the percutaneous absorption of diclofenac or its salts and provide good properties upon use and superior medical effects of diclofenac or its salts.Keywords
Diclofenac Sodium, Gel, Cream, Ointment, Diffusion Cell.
- Formulation and Evaluation of Polyherbal Anti-Acne Gel
Abstract Views :2698 |
PDF Views:1
Authors
A. C. Patil
1,
A. R. Patil
1,
A. C. Patil
1,
S. J. Shid
1,
V. N. Dange
1,
C. S. Magdum
1,
S. K. Mohite
1
Affiliations
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 8, No 2 (2017), Pagination: 61-63Abstract
Acne is an infection of the skin, caused by changes in the sebaceous glands. The most common form of acne is called acne vulgaris, which means "common acne". The redness comes from the inflammation of the skin in response to the infection. One of the most common disorders found among youngsters usually 18-25 years of age is Acne. Acne vulgaris, which is a skin disorder of the pilosebaceous gland leads to the formation of inflammatory lesions, seborrhea etc. There is a remarkable demand of herbal formulations in the global market. Acne is a popular disorder among the teenagers which make them feel unappealing to look at and also a sort of inferior feel. They take many measures to avoid and cure acne. Plants are well known for their medicinal and cosmetic uses.Keywords
Acne, Neem, Nutmeg.References
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- Kanlayavattanakul. M., Lourith N. Therapeutic agents and herbs in topical application for acne treatment. Int. J. Cosmetic Sci. 2011; 33:289-29.