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Synthesis, Characterization and Antimicrobial Screening of NewCyclic Imides


Affiliations
1 School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India
2 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India
     

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The Cyclic imides and their Derivatives have been attracted significantly more attention of organic and medicinal chemists due to their antimicrobial activities. The derivatives of six member cyclic imides were synthesized by the action of glutaric anhydride with different substituted aromatic amines to obtained 4-(N-phenylcarbamoyl) butanoic acid. These intermediates undergo ring closer with acetyl chloride furnished six member cyclic imides derivatives. All these derivatives were screened for their antimicrobial activities.

Keywords

Six Member Cyclic Imides, Glutarimide, 4-(N-Phenylcarbamoyl) Butanoic Acid, N-Phenyl.
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  • Synthesis, Characterization and Antimicrobial Screening of NewCyclic Imides

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Authors

Kulveer Singh
School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India
Suman Kumari
School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India
Y. K. Gupta
B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

Abstract


The Cyclic imides and their Derivatives have been attracted significantly more attention of organic and medicinal chemists due to their antimicrobial activities. The derivatives of six member cyclic imides were synthesized by the action of glutaric anhydride with different substituted aromatic amines to obtained 4-(N-phenylcarbamoyl) butanoic acid. These intermediates undergo ring closer with acetyl chloride furnished six member cyclic imides derivatives. All these derivatives were screened for their antimicrobial activities.

Keywords


Six Member Cyclic Imides, Glutarimide, 4-(N-Phenylcarbamoyl) Butanoic Acid, N-Phenyl.

References