Research Journal of Pharmacology and Pharmacodynamics

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Pathophysiology and Management of Diabetes:A Review


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1 Department of Pharmacology, Columbia Institute of Pharmacy, Tekari, Near Vidhansabha, Raipur- 493111(C.G.), India
     

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Diabetes mellitus is a very common metabolic disorder of endocrine system, every year large Number of people suffered from diabetes. According to recent survey in India about 50.8 million people are suffered from diabetes in 2010, and it will rise to 87.0 million till 2030. For the management and prevention of type 1 and type 2 diabetes different approaches have been done throughout the time In this article we have briefly discuss about evaluation of anti-diabetic activity by the use of different in vivo methods including animal model and in vitro method with special reference to cell line techniques. Article also reflect the evaluation of various anti diabetics phytoconstituents which is obtain from different plant source their activity, mechanism of action and it also highlight the advancement that has been done in past few year by different scientist their work title in different beta cell line technique and what output come from their effort to understand diabetes and to overcome it.

Keywords

Diabetes Mellitus, Pathophysiology, In-Vivo, In-Vitro Method, Treatment.
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  • Pathophysiology and Management of Diabetes:A Review

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Authors

Vandna Dewangan
Department of Pharmacology, Columbia Institute of Pharmacy, Tekari, Near Vidhansabha, Raipur- 493111(C.G.), India
Himanshu Pandey
Department of Pharmacology, Columbia Institute of Pharmacy, Tekari, Near Vidhansabha, Raipur- 493111(C.G.), India

Abstract


Diabetes mellitus is a very common metabolic disorder of endocrine system, every year large Number of people suffered from diabetes. According to recent survey in India about 50.8 million people are suffered from diabetes in 2010, and it will rise to 87.0 million till 2030. For the management and prevention of type 1 and type 2 diabetes different approaches have been done throughout the time In this article we have briefly discuss about evaluation of anti-diabetic activity by the use of different in vivo methods including animal model and in vitro method with special reference to cell line techniques. Article also reflect the evaluation of various anti diabetics phytoconstituents which is obtain from different plant source their activity, mechanism of action and it also highlight the advancement that has been done in past few year by different scientist their work title in different beta cell line technique and what output come from their effort to understand diabetes and to overcome it.

Keywords


Diabetes Mellitus, Pathophysiology, In-Vivo, In-Vitro Method, Treatment.

References