Different Electrodes for Paracetamol Estimation using Cyclic Voltammetry Technique:A Review

Paracetamol (N-acetyl p-aminophenol) is extensively used as an antipyretic and analgesic drug. It is an effective and safe molecule which is applied to reduce fever and pain including muscular aches, chronic pain, migraine headache, backache, and toothache. Generally, restricted use of paracetamol does not show any harmful side effects. However, overdosing and the chronic use of paracetamol generate toxic metabolite accumulation that will damage kidney and liver. So, a simple, accurate, sensitive, and fast analytical method for determining paracetamol in pharmaceutical preparations and human plasma is needed. Among the different methods, electro analytical methods are superior and voltammety is the good choice. In this review, different kinds of sensor electrodes in cyclic voltammetry technique are reported. This mini review is aimed at presenting an overview of the advances in the electrode material preparation.