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Sakthi Priyadarsini, S.
- Pharmacognostical Standardization of Leaves of Ravenala madagascariensis Sonn.
Authors
1 Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, Tamilnadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 288-292Abstract
Standardization was carried out on the basis of detailed botanical evaluation of the leaves which includes morphology and microscopy as well as WHO recommended physico-chemical studies. The results of the standardization may throw a immense light on the botanical identity of the leaves Ravenala madagascariensis Sonn., which may furnish a basis of judging the authenticity of the plant and also to differentiate the drug from its adulterants and other species.
Ravenala madagascariensis Sonn., (Strelitziaceae), also known as Visirivazhai in Tamil, is a native of Madagascar, widely cultivated for its distinctive habit in tropical and subtropical regions. In addition to its ornamental nature, this tree has been widely used in traditional medicine for the treatment of diabetes and kidney stone problems. The seeds are reported to be antiseptic. The leaves of Ravenala madagascariensis Sonn., have close resemblance with Musa leaf. Hence pharmacognostical standardization will contribute to the differentiation of Ravenala madagascariensis Sonn. leaves from that of Musa paradisiaca. The anatomy of leaf showed squarish upper epidermis. The lower epidermis was stomatiferous. Cyclocytic stomata, druses, raphides, mesophyll with tannin bodies, lobed sclereids remain the characteristic features of the leaf microscopy. Physicochemical parameters were evaluated and fluorescence analysis were carried out.
Thus the study employs the correct identification of standardization of the drug in crude form.
Keywords
Ravenala madagascariensis Sonn., Standardization, Botanical, Physico-Chemical Constants.
- Nitric Oxide Radical Scavenging Activity of the Ethanolic and Chloroform Extracts of Ocimum basilicum Linn. Leaves–A Comparative Study
Authors
1 Department of Pharmacognosy, SRM College of Pharmacy, Kattankulathur-603203, Tamilnadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 9, No 4 (2017), Pagination: 215-218Abstract
The aim of the present study is to investigate the efficiency of ethanolic and chloroform extracts of Ocimum basilicum Linn. leaves belonging to the family Labiatae for its in vitro antioxidant activity. The present study provides pharmacognostical, physicochemical and phytochemical details of the leaves of Ocimum basilicum which are useful in laying down standardization and pharmacopoeia parameters. In microscopic studies, transverse section (TS) of the leaves and its powder characters were studied and its characteristic features were established. Physicochemical parameters such as total ash value, acid insoluble ash value and water soluble ash value were determined. Preliminary phytochemical analysis of alcoholic extract and chloroform extract was carried out. The results of preliminary phytochemical screening were positive for flavonoids, carbohydrates, alkaloids, glycosides, proteins and saponin. The antioxidant potential of the chloroform and ethanol extract was evaluated using nitric oxide scavenging methods. It was found that the ethanolic extract showed better antioxidant effect compared to the chloroform extract.Keywords
Ocimum basilicum, Pharmacognostic, Microscopy, Antioxidant, Nitric Oxide Scavenging.References
- Gupta, Prakash SJ, Srivastav S. Validation of Claim of Tulsi, Ocimum sanctum Linn as a Medicinal plant. Journal of Experimental Biology. 2002; 40:765-773.
- Sen, P. Therapeutic Potential of Tulsi: From Experience to Facts. Drug News and Views. 1993; 1st ed: pp. 15-21.
- Choudhury GB, Behera M, Jena PK, Tripathy SK. Pharmacognostical and Phytochemical Investigation of Various Tulsi plants Available in South eastern Odisha. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2011; 2(2): 605-610.
- Sass JE, Elements of botanicals of microtechnique, New York, Mc Graw Hill and Co. 1998; pp. 222 – 225.
- Quality control methods for medicinal plant materials WHO, Indian edition, Geneva. 2004; pp. 28-30.
- Harborne, JB. Phytochemical methods, A guide to Modern Technique of Plant Analysis, Chapman and Hill, London. 1992.
- Kadifkova panovska T, Kulevanova S, Marina stefova. In vitro antioxidant activity of some Teucrium species (Lamiaceae). Acta Pharm. 2005; 55:207-214.
- Ganapathy S, Chandrasheka VM, Chitme HR, Lakashmi Narsu M. Antioxidant activity of gossypin and nevadensin. Indian Journal of Pharmacology. 2007;9(6):281-283.
- Malinski T. Nitric oxide and nitroxidative stress in Alzheimer's disease. Journal of Alzheimer’s Disease. 2007;11:207-218.
- Szabó C, Ischiropoulos H, Radi R. Peroxynitrite: Biochemistry, Pathophysiology and development of therapeutics. Drug discovery. 2007; 6: 662.
- Burney S, Niles JC, Dedon PC, Tannenbaum SR. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chemical Research in Toxicology. 1999; 12: 513‐520.
- Rekha Rajendran, N Saleem Basha and S Ruby. Evaluation of In Vitro Antioxidant Activity of stem-bark and stem-wood of Premna serratifolia Lin., (Verbenaceae). Research journal of Pharmacognosy and Phytochemistry. 2009;1(1):11-14.
- Nirmala Shinde, R.A. Saindane, S.K. Bhosale and Shreenivas Deshpande. In vitro Antioxidant Activity of Ethanolic and Chloroform Extracts of Tagetes erecta Flowers. Research journal of Pharmacognosy and Phytochemistry. 2010;2(4):324-326.
- Njoku Obioma U., Joshua Parker Elijah and Okonkwo Chukwudi C. Antioxidant Properties of Gongronema latifolia. Asian Journal of Research Chemistry. 2011; 4(9): 1411-1414.
- Dibyajyoti Saha* and Ankit Tamrakar. Xenobiotics, Oxidative Stress, Free Radicals vs. Antioxidants: Dance of Death to Heaven’s Life. Asian J. Res. Pharm. Sci. 1(2): April-June 2011; Page 36-38