Research Journal of Pharmacognosy and Phytochemistry

P. Nagaveni ¹, G. Krishna Mohan ¹, Switi B. Gaikwad ¹

Affiliations
1 Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad-500 085, Telangana, IN

Abstract

Medicinal plants are the most exclusive source of life saving drugs for the majority of the world's population. The pharmacological evaluation of substances from plants is a method for the discovery of new compounds which can leads to the development of novel and safe medicinal agents. Based on traditional literature, Maytenus emarginata (Celastraceae) is an evergreen tree, commonly known as "thorny staff tree" in English. In present study the leaves and stems of Maytenus emarginata were extracted with methanol to produce respective extracts. The extracts were screened for anti cancer activity by using Antimitotic activity by Allium cepa method, Seed germination assay by green gram seeds and Brine shrimp lethality test using Artemia salina eggs. Methotrexate was used as standard anticancer drug. Current study demonstrates that the obtained results of leaves extracts were more potent than the stems extracts.

Keywords

Maytenus emarginata, Celastraceae, Thorny Staff Tree, Antimitotic Activity.

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E. Swapna ¹, G. Krishna Mohan ¹, P. Nagaveni ¹, Kalakotla Shanker ¹

Affiliations
1 Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad-500 085, Telangana, IN

Abstract

Ayurvedic medicine or Ayurveda is one of the world's ancient medical systems. It originated in India and has evolved here over thousands of years. The term "Ayurveda" combines the Sanskrit words ayur (life) and veda (science or knowledge) which means "The science of life". Ayurveda was the first holistic system of diagnosis, treatment integrating nutrition, hygiene, rejuvenation and herbal medicine. Balarishta is a poly herbal hydro alcoholic preparation and is used to cure gastric problems as restorative and as prime tool for the treatment of Arthritis, Rheumatism and all other auto immune disorders. In present study the Balarishta formulations (B1, B2, and B3) were screened for the Antioxidant activity by using Reducing Power Assay, Hydrogen Peroxide Scavenging Assay, Nitric Oxide Scavenging Assay methods. Ascorbic acid was used as standard Antioxidant drug. Current study demonstrates that the obtained results of Balarishta formulation was showed the good Antioxidant activity near to compared with standard drug.

Keywords

Ayurveda, Balarishta, Antioxidant Activity, Hydrogen Peroxide Scavenging Assay, Nitric Oxide Scavenging Assay, Ascorbic Acid.

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