Research Journal of Pharmacognosy and Phytochemistry

V. R. Ravikumar ¹, T. Sudha ², P. V. Hemalatha ²

Affiliations
1 Department of Pharmacognosy, The Erode College of Pharmacy, Erode-638112, IN
2 Dept. of Pharma. Analysis, The Erode College of Pharmacy and Research Institute, Erode-638112, Tamilnadu, IN

Abstract

Spirulina platensis (fam: Cyanophyaceae) is a blue green fresh water algae. It is a simple, single - celled alga that thrives in warm alkaline fresh water. It is helical in shape and hence the name Spirulina. Spirulina is being developed as the food of the future due to its very high nutritional value. The present work deals with identification of the different constituents of Spirulina using HPTLC finger printing. The dried form of algae was used to prepare extracts of Spirulina in different polar and non polar solvents like petroleum ether, chloroform, ethyl acetate, ethanol and water. The extracts were then subjected to different chemical tests. The ethanol extract presented a good result for the presence of alkaloids, flavonoids and steroids. The ethanol extracts was then subjected to HPTLC analysis in various solvents, suitable for alkaloids, flavonoids and steroids. The HPTLC fingerprinting results confirmed the presence of alkaloids, flavonoids and steroids.

Keywords

Spirulina platensis, HPTLC, Alkaloids, Flavonoids, Steroids, Immunomodulatory.

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V. R. Ravikumar ¹, T. Sudha ², P. V. Hemalatha ²

Affiliations
1 Department of Pharmacognosy, The Erode College of Pharmacy, Erode-638112, IN
2 The Erode College of Pharmacy and Research Institute, Erode-638112, Tamilnadu, IN

Abstract

Spirulina plantensis (fam: cyanophyaceae) is a blue green fresh water algae. It is a simple, single- celled alga that thrives in warm alkaline fresh water. It is helical in shape and hence the name spirulina. Spirulina is being developed as the food of the future due to its very high nutritional value. The extracts were then subjected to antibacterial studies using Muller Minton agar and fresh strains of E. coli and Staphylococcus aureus and Ciprofloxacin as the standard drug. Antifungal studies were perform using potato dextrose agar medium and fresh strain of Aspergillus niger and Griseofulvin, as the standard drug cup diffusion method was followed for both the studies. It was found that when compared with standards and among the extracts, the ethanol extract showed a significant antibacterial and antifungal activity.

Keywords

E.coli, Staphylococcus aureus, Aspergillus niger, Griseofulvin, Spirulina platensis, Ciprofloxacin, Anti Microbial.

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