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Chitra, M.
- In vitro Anti-Inflammatory Activity of Drynaria quercifolia Rhizome
Authors
1 P.G and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College, Mannargudi, Thiruvarur Dt, Tamil Nadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 7, No 1 (2015), Pagination: 6-8Abstract
In the present study, the methanolic extract of Drynaria quercifolia rhizome was investigated for its anti inflammatory activity by Human Red Blood Cell (HRBC) Membrane stabilization method. Different concentration (100, 200 and 300 mcg) of rhizome extract were used and the potency of extract was compared with standard Diclofenac (100, 200 and 300 mcg). Plant extract exhibited notable anti-inflammatory activity in a dose dependent manner. The maximum membrane stabilization was found to be 34.94% for plant extract and 41.62% for standard Diclofenac at a dose of 300 mcg. In conclusion, the results thus obtained suggested that rhizome of Drynaria quercifolia possess considerable antiinflammatory activity and therefore further in vivo studies are needed to establish it as a potent anti-inflammatory agent.Keywords
Anti-Inflammatory, Drynaria quercifolia, Methanolic Extract, Membrane Stabilization.
- In-vitro Anti Oxidant and Antimicrobial Activities of Ethyl Acetate Extract of Evodia lunu-Ankenda (Gaertn) Merr. Bark
Authors
1 Department of Pharmaceutical Chemistry, JKKMMRF College of Pharmacy, B. Komarapalayam, Tamil Nadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 201-203Abstract
In this paper, in vitro antioxidant and antimicrobial activities of ethyl acetate extract of Evodia lunu-ankenda (Gaertn) Merr. bark was determined by four methods Diphenylpicrylhydrazyl (DPPH), Nitric Oxide, Super oxide disumatase, Hydrogen peroxide (H2O2) and by agar disc diffusion methods. The crude ethyl acetate extract of Evodia lunuankenda bark inhibited the growth of both gram positive bacteria (Bacillus substilis, Staphylococcus aureus and micrococcus luters) and gram negative bacteria (Escharichia coil, Pseudomonas aeruglinosa and Salmonella typhlmurium) and also the crude ethyl acetate extract of Evodia lunuankenda bark inhibited the growth of fungi (candida albicans and Aspergillus niger). The ethyl acetate extract of Evodia lunuankenda bark showed dose dependent increase in reducing anti oxidant power that was comparable to standards. Antibacterial activity, highest concentration of ethyl acetate extract (5mg/ml) having good activity against gram positive and gram negative organisms as compared with the reference Ciprofloxacin. Antifungal activity, highest concentration of extract (5mg/ml) having good activity as compared with the reference Amphotericin-B. It can be concluded that the plant posses potent antioxidant and antimicrobial activity, responsible of the secondary metabolites like flavonoids, saponins, are likely observed for the plants.