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Padhi, M. M.
- Evaluation of Quality Control Parameters for Srngyadi Churna – A Potential Ayurvedic Formulation
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Authors
Affiliations
1 National Research Institute for Ayurveda - Siddha Human Resource Development, Gwalior, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala, IN
3 National Research Institute of Ayurvedic Drug Development, Bhubaneswar, IN
4 Ayurveda Central Research Institute - New Delhi, IN
5 Central Council for Research in Ayurvedic Sciences, New Delhi-110058, IN
1 National Research Institute for Ayurveda - Siddha Human Resource Development, Gwalior, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala, IN
3 National Research Institute of Ayurvedic Drug Development, Bhubaneswar, IN
4 Ayurveda Central Research Institute - New Delhi, IN
5 Central Council for Research in Ayurvedic Sciences, New Delhi-110058, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 5, No 1 (2013), Pagination: 42-46Abstract
Standardization of Ayurvedic formulations is essential in order to assess the quality, purity, safety and efficacy of drugs based on the amounts of their active principles. The present research work is an attempt to standardize “Srngyadi Churna” an ayurvedic polyherbal formulation used in the treatment of cough, asthma and fever. The formulation was prepared in institute pharmacy as per Ayurvedic formulary of India, Part- I guide lines and attempts to evaluate the organoleptic characters, phamacognostic study and physicochemical parameters like pH, Loss on drying at 105°C, Water soluble extract, Alcohol soluble extract, Total Ash, Acid insoluble ash and TLC. The study revealed specific identities for crude drug taken which will be useful in identification and control to adulterations of the drugs.Keywords
Srngyadi Churna, Standardization, Ayurveda, Asthama, Formulation.
References
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- Anonymous, Indian Herbal Pharmacopoeia, A joint Publication of Regional Research Laboratory, Jammu Tawi and Indian Drug Manufacturer’s Association, Mumbai, 1999, 93.
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- AOAC official methods of analysis of AOAC International, 16th edition. AOAC International, Suite 400, 2200 Wilson Doulevard, Arlington, Virginia, USA, 1995.
- Anonymous the Ayurvedic Pharmacopoeia of India, Part – II (formulations) Volume – II, 1st edition, Government of India, Ministry of health and family welfare, Department of AYUSH, New Delhi, 2008.
- Meena A. K., Rao M M, Panda P, Kiran, Yadv Ajay, Singh Uttam, Singh B Standardisation of Ayurvedic Polyherbal Formulation, Pancasama Churna. International Journal of Pharmacognosy and Phytochemical Research. 2010, 2 (1).
- Meena A. K. Kaur Ramanjeet, Singh Brijendra, Sachan Ayushy, Pal Bhavana, Singh R, Rao M M. “Evaluation of Standardisation Parameters of Ashwgandha Churna – Ayurvedic Drug” Journal of Pharmacy Research, 2010, 3(4), 831-832.
- Meena A. K., Mangal A. K., Rao M. M., Panda P., Simha G. V., Shakya S. K., Padhi M. M. and Babu Ramesh. Evaluation of Standardization Parameters for Sitopaladi Churna an Ayurvedic Formulation. Asian J. Research Chem. 2011, 4(12): 1867-1871.
- Simple, Rapid and Precise Method for Quality Assessment of Different Parts of Aegle marmelos L. Used in Indian System of Medicine
Abstract Views :166 |
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Authors
Affiliations
1 Central Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp.-D-Block, Janakpuri, New Delhi-110058, IN
2 Arbro Pharmaceuticals (Pvt.) Limited, Kirti Nagar, New Delhi, IN
1 Central Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp.-D-Block, Janakpuri, New Delhi-110058, IN
2 Arbro Pharmaceuticals (Pvt.) Limited, Kirti Nagar, New Delhi, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 5, No 5 (2013), Pagination: 236-243Abstract
Aegle marmelos (L.) Corr. Serr, family Rutaceae is an important medicinal plant and immensely used in the Indian System of Medicine to cure human diseases. Plant parts like ischolar_main, stem bark and fruit have been reported for various medicinal properties such as anti-diabetic, anticancer, anti bacterial, anti fungal, anti pyretic, analgesic, antioxidant, cardio protective, radio protective, anti-diarrheal, anti-dysentery, anti-ulcer, wound healing and many more. A. marmelos is commonly known as a bael in India. Chemo-profiling screening on different parts of A. marmelos plants revealed variations in phytochemicals within different parts of plant. The unique properties of the chromatographic fingerprint were validated by analyzing ischolar_main, stem bark and fruit of A. marmelos. Our results revealed that the chromatographic fingerprint combined with similarity measurement could efficiently identify and distinguish A. marmelos from the other investigated Aegle species. In this paper a new, simple method is proposed in which the TLC pattern of the extracts of ischolar_main, stem bark and fruit of A. marmelos content is used for effective and reliable quality control of the drug. The method can also be used for identification of different A. marmelos species. The proposed method uses cold-extraction then clean-up by solid-phase extraction before chromatographic analysis. The results revealed that the retention factor (Rf) of A. marmelos stem bark, ischolar_main and fruit furnishes a specific TLC chromatogram fingerprint which might be helpful for quality assurance and detection of adulteration of crude extracts. The ischolar_main, stem bark and fruit of A. marmelos L. were also physico-chemically standardized as per WHO specification.Keywords
Aegle marmelos L., Chemo-Profiling, TLC–UV Detection, Physicochemical Analysis.- HPTLC Profile of Important Indian Spices used in Ayurvedic Formulations
Abstract Views :202 |
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Authors
Affiliations
1 NRIASHRD, CCRAS, Aamkho, Gwalior, (MP), IN
2 National Research Institute for Ayurveda- Siddha Human Resource Development, Gwalior, IN
3 Central Council for Research in Ayurvedic Science, Janakpuri, Delhi –110058, IN
4 Central Council for Research in Ayurvedic Science, Janakpuri, Delhi – 110058, IN
1 NRIASHRD, CCRAS, Aamkho, Gwalior, (MP), IN
2 National Research Institute for Ayurveda- Siddha Human Resource Development, Gwalior, IN
3 Central Council for Research in Ayurvedic Science, Janakpuri, Delhi –110058, IN
4 Central Council for Research in Ayurvedic Science, Janakpuri, Delhi – 110058, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 5, No 4 (2013), Pagination: 188-193Abstract
Plant derived spices are generally used in foods for flavoring and medicinal purposes. Spices have been shown to possess medicinal value, such as antimicrobial activity, antioxidant, anticancer, anti-inflammatory activity etc. Several spices particularly Tejpatta (Cinnamomum tamala), Souff (Foeniculum vulgare), Jeera (Cuminum cyminum), Methi (Trigonella foenum-graecum), Ajwain (Trachyspermum ammi), Dhaniya (Coriandrum sativum), Kali Mirch (Piper nigrum), Kalonji (Nigella sativa) are used extensively in the Indian diet and in ayurvedic medicines. Development of standard procedure through HPTLC is a new approach which may lead to proper standardization of different spices and ayurvedic drugs based on fingerprinting characteristics. HPTLC Fingerprinting technique is widely employed in pharmaceutical industry in process development, identification and detection of adulterants in herbal product and helps in identification of pesticide content, mycotoxins and in quality control of spices and herbs. The study revealed specific identities for spices/herbal drugs taken which will be useful in identification and control to adulterations of the drugs.Keywords
Spices, Herbal Drugs, Quality Control, HPTLC Fingerprints, Ayurvedic Medicines.- Comparative Studies on Quality Assessment of Trachyspermum Ammi Linn. Seeds Collected from Different locations of Punjab State
Abstract Views :171 |
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Authors
Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala -147001, IN
2 National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala -147001, IN
3 Raja Ramdeo Anandilal Podar Ayurveda Cancer Research Institute, Mumbai, IN
4 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
5 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi- 110058, IN
1 National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala -147001, IN
2 National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala -147001, IN
3 Raja Ramdeo Anandilal Podar Ayurveda Cancer Research Institute, Mumbai, IN
4 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
5 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi- 110058, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 3, No 1 (2011), Pagination: 41-44Abstract
Ayurveda, the science of life, deals with the holistic view of healthy living. It emphasizes on prevention as well as treatment of various disease conditions through holistic approach. Since ancient times, several diseases have been treated by administration of plant material based on traditional method and approaches. Investigation of traditionally used medicinal plants is thus valuable on two levels, firstly, as a source of potential chemotherapeutic drugs, and secondly, as a measure of safety for the continued use of medicinal plants. The seeds of Trachyspermum ammi Linn. are being used in traditional folk medicines for the treatment of various gastro-intestinal and inflammatory disorders. It is a bitter, aromatic, thyme like aroma warming herb, and possesses tonic, diuretic, and expectorant properties. It relaxes spasms, improves digestion, increases perspiration and is a strong antiseptic. Physicochemical studies on various parameters like total ash, acid insoluble ash, water soluble ash, ethanol soluble extractive value, water soluble extractive value, loss on drying, pH, TLC reveal specific identities for the crude drug which will be useful in identification and help in controlling adulterations.Keywords
Ayurveda, Thymol, Phytochemistry, Trachyspermum ammi Linn.- Comparative Study of Various Plants of Piperaceae Family Commonly Used in Ayurvedic Formulations
Abstract Views :153 |
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Authors
Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala – 147001, Punjab, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Patiala-147001, Punjab, IN
3 National Institute of Ayurveda, Jaipur, IN
4 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
1 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala – 147001, Punjab, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Patiala-147001, Punjab, IN
3 National Institute of Ayurveda, Jaipur, IN
4 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 5 (2010), Pagination: 407-410Abstract
The present article attempts to compare TLC and physico-chemical parameters of P. nigrum Linn., Piper cubeba Linn., Piper longum Linn. and Piper chaba Hunter belonging to common family piperaceae. Each of them is considered to have huge medicinal value in Ayurveda, Sidhha and Unani traditional medicines. Since ancient times, these drugs are used according to their medical value. Investigation of such traditionally used medicinal plants is thus valuable on two levels, firstly, as a source of potential chemo therapeutic drugs and secondly, as a measure of safety for the continued use of medicinal plants.
The present paper attempts to evaluate the physicochemical parameters like pH, Loss on drying at 105°C, Water soluble extract, Alcohol soluble extract, Total Ash, Acid insoluble ash and thin layer chromatography. The study revealed specific identities for crude drug taken which will be useful in identification and control to adulterations of the raw drug.