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Authors
Affiliations
1 St. Ann’s College of Pharmacy, Nayunipalli, Chirala - 523187, Prakasam District, Andhra Pradesh, IN
2 Vels University, Chennai, IN
3 Research and Development Center, Rumi Herbals Pvt. Ltd., Mugappair, Chennai, IN
4 Department of Pharmacognosy, Sri Ramachandra University, Porur, Chennai - 600 116, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 3, No 3 (2011), Pagination: 128-133
Abstract
The stability studies of the polyherbal capsules of Urito, (recommended for urinary stones and urolithiasis) were performed under accelerated conditions of temperature and humidity in a stability chamber. The study was done for a period of 105 days under stable accelerated conditions and samples were taken on every 15th day for analysis. Various parameters like ash values, extractive values, total tannin content, mucilage content, loss on drying, weight variation and disintegration time were determined on 0, 15th, 30th, 45th, 60th, 75th, 90th and 105th days of the study period and were compared with the values of the already obtained (in-house) standard limits of the formulation. The results have shown that there was no significant difference in the values obtained when compared with the standard values except for very slight variations which were within the limits of the standard values. Thus it was concluded that the polyherbal capsules of Urito will be stable for a period of 2 years without losing intactness of its contents. This could be further confirmed by real time stability studies.
Keywords
Stability Studies, Stability Chamber, Accelerated Conditions, Polyherbal Capsules.
