Research Journal of Pharmacognosy and Phytochemistry

Ravindra Singh ¹, Aakanksha Tiwari ¹

Affiliations
1 Department of Biological Science, Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalya, Chitrakoot, Satna (M.P) Pin-488334, IN

Abstract

Adhatoda vasica belonging to Acanthaceae family, commonly known as Adosa, is found in many regions of India and throughout the world, with a multitude of uses in traditional Ayurveda. Vasica is most well-known for its effectiveness in treating respiratory conditions and are highly demandable in pharmaceutical industries. The compound isolated from ethyl acetate fraction of Adhatoda vasica flowers extract has a significant antibacterial activity against bacteria and fungi. Four bacterial strains like S. typhi, E. coli, E. faecalis and B. cereus and two fungal strains such as C. lunata and C.albicans were tested by using disc diffusion method. The anti bacterial activity of the compound isolated from ethyl acetate fraction is almost comparable with the standard Chloramphenicol and the anti-fungal activity of the compound isolated from ethyl acetate fraction is almost comparable with the standard Fluconazole. These are the drugs from Adhatoda vasica flowers that either destroy or inhibit the growth of bacteria and fungi. It has also the ability to prevent or treat bacterial and fungal infections. Further studies are highly needed for future drug development. The present research aims to compile medicinal values of Adhatoda vasica flowers generated through the research activity using modern scientific approaches and innovative scientific tools.

Keywords

Adhatoda vasica, Pharmacology, Asthma, Traditional Medicine.

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Ashok Kumar Tiwari ¹, Neelesh Dwivedi ¹, Manoj Kumar Tripathi ¹, Aakanksha Tiwari ¹, Pawan Kumar Ahirwar ¹, Sharda Prasad Tripathi ¹

Affiliations
1 Ayurveda Sadan, Arogyadham, JRD Tata Foundation for Research in Ayurveda and Yoga Sciences, Deendayal Research Institute, Chitrakoot, Satna, Madhya Pradesh-485334, IN

Abstract

Ayurvedic medicine Kutajastaka Pravahi Kvatha, known to be effective in Daha (burning sensation); Raktatisara (Diarrhoea with blood); Sula (pain); Amadosa; (products of impaired digestion and metabolism) and Sarvatisara (all types of diarrhoea), has been standardized by following modern scientific quality control procedures for the finished product. The results of physico-chemical parameters viz. specific gravity (1.01), total solids (4.45%) and pH (4.50) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopiea of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Kutajastaka Pravahi Kvatha facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in understanding the underlying mechanism of pharmacological action.

Keywords

Standardization, Ayurvedic Formulation, Kutajastaka Pravahi Kvatha, Pharmacopoeial Standards.

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Ravindra Singh ¹, Aakanksha Tiwari ¹

Affiliations
1 Department of Biological Science, Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya, Chitrakoot-488334, Satna (M.P), IN

Abstract

Clerodendrum serratum is a shrub which is not much branched with stems. The ischolar_main of the plant is attributed with various activities like anti-inflammatory, digestive and carminative and many more. It is used to treat the conditions like inflammations, anorexia, cough, asthma, hiccough, tubercular glands, skin diseases etc. Various minerals like Na, Mg, Al, Ca etc. saponins, terpenoids, D-mannitol are the phytoconstituents present in the plant. Research works are carried out to study the pharmacognostic, physicochemical, hepatoprotective, anti-oxidant, anti-inflammatory, analgesic, antiasthmatic and various other activities. Clinical trial was also done in patients of Tamaka shwasa (Bronchial asthma). Thus, this paper highlights the various pharmacological activities of Clerodendrum serratum and its further scope for clinical utility.

Keywords

Cleodendrum serratum, Pharmacology, Asthma, Traditional Medicine.

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