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Authors
Affiliations
1 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, A/P- Loni, Tal -Rahata, Dist- Ahmednagar, Pin- 413736, Maharashtra, IN
2 Dep. of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, IN
3 Dep. of Pharmacology, Pravara Rural College of Pharmacy, Pravaranagar, IN
4 Deparrment of Pharmacognosy, M.M. College of Pharmacy, Pune, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 220-223
Abstract
Achyranthes aspera is common weed found in India and has great medicinal importance. The plant is beneficial in various ailments including stomachache, piles, boils, skin eruption and in asthma. It is also used as anti-inflammatory and as immunomodulator drug. It may act on reactive oxygen species which are one of the factor in the pathogenesis of these diseases. Various extracts of A. aspera, viz., petroleum ether extract, chloroform extract, ethyl acetate extract, ethanol extract and aqueous extract were screened for the antioxidant activity of the plant by using DPPH assay, ABTS assay and FRAP assay. Among all these extracts petroleum ether extract was found to be active as it shows lowest IC50 value in DPPH assay and highest trolox equivalent antioxidant concentration (TEAC) in ABTS assay and FRAP assay. Phytochemical screening revealed that as flavonoids, tannins and phenolic compound are absent in the plant, nonpolar compounds like steroids may be responsible for the antioxidant activity of the plant.
Keywords
Achyranthes aspera, DPPH Assay, ABTS Assay, FRAP Assay.
