Research Journal of Pharmacognosy and Phytochemistry

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Comparative Evaluation of Anthelmintic Potential of Cucurbita maxima Seeds, Moringa oleifera Seeds and Solanum surattense Fruits


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1 Maharajah's College of Pharmacy, Phoolbaugh, Vizianagaram, Andhra Pradesh, India
     

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The medicinal plants are widely used by the traditional medical practitioners for curing various diseases. Helminthiasis is the most common infection in human affecting a large proportion of world population. Parasitic diseases may cause severe morbidities including lymphatic filariasis and onchocerciasis. Development of resistance to most of the commercially available anti helminthiasis becomes a severe problem worldwide. The present study was under taken to evaluate antihelmenthic activity of ethanol extract of seeds of Cucurbita maxima, Moringa olifera and fruits of Solanum surattense on Indian earthworm pheritima phosthuma. Various concentrations (10, 25, 50 mg/ml) of extracts were tested and results were expressed in terms of time of paralysis and time of death of the worm. Piperazine citrate (10 mg/ml) is used as reference standard and saline water as control.

Keywords

Antihelmenthic Activity, Pheritima Posthuma, Cucurbita maxima, Moringa olifera, Solanum surattense.
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  • Comparative Evaluation of Anthelmintic Potential of Cucurbita maxima Seeds, Moringa oleifera Seeds and Solanum surattense Fruits

Abstract Views: 320  |  PDF Views: 2

Authors

Saroj Kumar Raul
Maharajah's College of Pharmacy, Phoolbaugh, Vizianagaram, Andhra Pradesh, India
Gopal Krishna Padhy
Maharajah's College of Pharmacy, Phoolbaugh, Vizianagaram, Andhra Pradesh, India
Soudamini Alekha Charan
Maharajah's College of Pharmacy, Phoolbaugh, Vizianagaram, Andhra Pradesh, India
Neelima Gurubarik
Maharajah's College of Pharmacy, Phoolbaugh, Vizianagaram, Andhra Pradesh, India

Abstract


The medicinal plants are widely used by the traditional medical practitioners for curing various diseases. Helminthiasis is the most common infection in human affecting a large proportion of world population. Parasitic diseases may cause severe morbidities including lymphatic filariasis and onchocerciasis. Development of resistance to most of the commercially available anti helminthiasis becomes a severe problem worldwide. The present study was under taken to evaluate antihelmenthic activity of ethanol extract of seeds of Cucurbita maxima, Moringa olifera and fruits of Solanum surattense on Indian earthworm pheritima phosthuma. Various concentrations (10, 25, 50 mg/ml) of extracts were tested and results were expressed in terms of time of paralysis and time of death of the worm. Piperazine citrate (10 mg/ml) is used as reference standard and saline water as control.

Keywords


Antihelmenthic Activity, Pheritima Posthuma, Cucurbita maxima, Moringa olifera, Solanum surattense.

References