Open Access Subscription Access
Open Access Subscription Access
Investigation on the Antimicrobial and Antioxidant Activity of Custard Apple (Annona reticulata) Peel Extracts
Background: Custard apple or sugar apple can be called as a delicacy of dry region due to its very sweet delicate flesh. The peel of custard apple contains tannins, acetogenin and alkaloids which is beneficial in the treatment of several types of cancer and tumors. Methodology/Principal Findings: The present study was taken up to investigate the phytochemical composition, antimicrobial potential, antioxidant activity of the fruit peel wastes of custard apple. The phytochemical screening of the fruit peel revealed the presence of Carbohydrates, Saponins, Phenols and Terpenoids .The antioxidant property of the peel extract was evaluated using DPPH free radical scavenging and FRAP assay. The antimicrobial test results showed that the raw fruit peel extract had a great potential antimicrobial activity against all the bacteria and fungal species selected for testing.Conclusions/Significance: The results presented here may suggest that the raw fruit peel extracts possesses antioxidant and antimicrobial properties, and is therefore a potential source of ingredients for the food and pharmaceutical industry.
Annona reticulata, Antimicrobial, Antioxidant.
- Annie S, Rajendran K Dinesh Kumar V and Ramgopal B. Antidiabetic activity of aqueous leaf extracts of Annona reticulata in streptozotocin–nicotinamide type 2 diabetic rats. Journal of Ethnopharmacology. 2004; 91: 171–175.
- Vijay K and Sriram S, Antioxidant activity of seed extracts of Annona reticulata and Carica papaya. Nutrition and Food Science. 2010; 40 (4): 403-408.
- Vohar, SB, Ishwar Kumar and Naquvi SA. Phytochemical, Pharmacological, antibacterial and anti-ovulatory studies on Annona squamosa. Planta Med. 1975; 28: 97-100.
- Zhao GX, Rieser MJ, Hui YH, et al. Biologically active acetogenins from stem bark of Asiminatriloba. Phytochemistry.1993; 33(5):1065-1073.
- Fang C, Jien C, Chih-Yuan L, Hui-Fen C, Ming-Juan W, and Yang-Chang W. Bioactive acetogenins from the seeds of Annona atemoya. Phytochemistry.1999 51: 883-889.
- Wiart C, Au T.S, Mohd Y, Hamimah, H. and Sulaiman, M. An antibacterial diterpene from sweet apple (Annona reticulata L. Annonaceous). International Journal of Pharmacology.2005: 1 (3) :296-298.
- Trease and Evans. Text book of Pharmacognosy 13 th Edition 1989
- Niwano Y, Beppu, F, Shimada T, Kyan R, Yasura K, Tamaki M, Nishino M and Hamada, H. Extensive screening for plant foodstuffs in Okinawa, Japan with anti-obese activity on adipocytes in vitro. Plant Foods Human Nutrition. 2009; 64:6-10.
- Chang CJ and Mc Laughlin, J. L. Structure-activity relationships of diverse Annona ceousacetogenins against multi-drug resistant human mammary adenocarcinoma (MCF-7/Adr) cells. Journal Medical Chemistry. 1997; 40; 2102-2106.
- George A, Broadley R, and Nissen, R. Preliminary review of the health and medicinal benefits of Annona spp. possible paths to commercialisation. A confidential report for the Australian Custard Apple Growers Association. (2006).
- Alali, Liu, X and McLaughlin, J. L. Annonaceousacetogenins: recent progress. Journal of Natural. Products. 1999; 62: 504-540.
- Bonavia D, Ochoa C, Tovar S, and Palomino R. Archaeological evidence of cherimoya (Annona cherimola Mill.) and guanabana (Annona reticulata L.) in ancient Peru. Economic Botany. 2004; 58(4): 509-522.
- Kaleem M, Asif M, Ahmed Q and Bano, B. Anti-diabetic and antioxidant activity of Annona squamosa extract in streptozotocin-induced diabetic rats. Singapore Medical Journal. 2006; 47(8): 670-675.
Abstract Views: 27
PDF Views: 0