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- Mukesh Sharma
- V. Minu
- Kushagra Nagori
- Anjali
- Manish Dewangan
- Sagufta Magar Richa Khan
- D.K. Tripathi
- Nisha Nair
- Amrita Thakur
- Mukta Agrawal
- Juhi Thakur
- Shubhangi Gupta
- Bharti Sahu
- Devendra Kumar
- Indu Rai
- Jaya Sonkar
- Kalyani Sahu
- Kuldeep
- Kailash Kumar
- Muktanand
- Nidhi Kaushik
- Omkar Sahu
- Somsunder Sahu
- Umesh Kumar
- D. K. Tripathi
- Amit Alexander
- Yashi Thakur
- Teman Nirmalkar
- Ved Prakash Verma
- Vibhash Gupta
- Vivek Singh Yadav
- Kalpana Mahilange
- Pooja Mahant
- Pritam Yadav
- Deepak Patel
- Dinesh Khamari
- Jyotsana Meshram
- Rakesh Sahu
- Tarun Ghatode
- Shubham Tripathi
- Somnath Patel
- Ritesh Patel
- Shraddha
- Pushpendra
- Sachin
- Neetish
- Mahendra
- Prashant
- Rajesh Patel
- Girish
- Nitin
- Tomanlal
- Umesh Kumar Sahu
- Ranjeeta Kumari
- Harish Sharma
- Gyanesh Kumar Sahu
- Ayushmaan Roy
- Anjali Wahane
- Siddharth Karankal
- Prachi Sharma
- Davesh Khutel
- Onkarnath Singh
- Vinay Shardul
- Pitamber
- Nausheen Sabha
- Jyoti Dewangan
- Ajay Dewangan
- Akash Jangde
- Chaya Rani
- Tekeshwar Sahu
- Gyanesh Sahu
- Priya Patel
- Rohini Sahu
- Renjil Joshi
- Surabhi Armarkar
- Tarannum Parveen
- Narendra Pratap
- Renuka Sahu
- Pushpanjali Sahu
- Dujram Sahu
- Rupali Manikpuri
- Madhav Patel
- Tikeshwar Sahu
- Bhupendra Rajak
- Parmanand Sahu
- Pooja Yadav
- Alok Ranjan
- Aishwarya Sahu
- Akansha Yadav
- Alka Payasi
- Akash Jaiswal
- Akshay Kumar
- Akash Sahu
- Ashwani Jangde
- Chandrashekhar Nayak
- Dev Kumar
- Harshita Yarda
- Mitali Sahu
- Nokesh Sahu
- D. K. Tripathi
- Kritika Kanoujia
- Chandraprabha Dewangan
- AyushI Masih
- Dipti Sinha
- Divya Oraon
- Manisha Jaiswal
- Monika Sahu
- Sapna Pradhan
- Ravi Suman
- Rajkishan Dewangan
- Roman Banjare
- Pradeep Paikra
- Mukesh Rawtiya
- Khuman Lal
- Navneet Patel
- Lekhraj
- Jai Prakash
- Omkar
- Rakesh Gurjar
- Achyutanand Gupta
- Chandra Prakash
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
, Ajazuddin
- A Survey on College Student Lifestyle: Bhilai City 2011-12
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Authors
Mukesh Sharma
1,
Ajazuddin
1,
V. Minu
1,
Kushagra Nagori
1,
Anjali
1,
Manish Dewangan
1,
Sagufta Magar Richa Khan
1,
D.K. Tripathi
1
Affiliations
1 Rungta Collage of Pharmaceutical Science and Research, Kurud, Bhilai- 490026 (C.G.), IN
1 Rungta Collage of Pharmaceutical Science and Research, Kurud, Bhilai- 490026 (C.G.), IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 5, No 1 (2013), Pagination: 34-39Abstract
Students are young and their behavior can reflect the health status of the society they are going to live in the coming years. Lifestyle reflects social values, attitudes and activities of a person. Personal health is a function of lifestyle and behavior, which can be altered through medical device. The unhealthy lifestyle, common in modern societies, accounts for a high number of mortalities secondary to preventable diseases. The aim of the current study was to explore the students’ lifestyle in order to formulate policies and educational and behavioral programs to promote their overall wellbeing. Data were collected by mailed questionnaires in 2011 Jan–March from a Local sample of Bhilai City, State-Chhattisgarh having age group of , 18-21 years old. In this, only the 18 year old & above considered, however, there are no means to assess representativeness according to college performance. It has been found that in health-related surveys the response rate is lower in young boy than in young girl, and that reluctance to respond is associated with negative health behavior and poor college performance. If active responding were selective in that direction also here, the associations found would be weak as compared to the situation where everyone would have responded. We have found that addiction of pan was more in college A as compared to college B, C, and D and also B+ blood group of college A was more as compared to college B,C and D. Disease history of cancer in college C was more as compared to college A and B.Keywords
Survey, Students, Life Style, College, Chhattisgarh.References
- Westerberg J, Jason H. Fostering healthy behavior (the process) In: Wolf SH. Editor. Health promotion and disease prevention. Baltimore: Lippincott Williams and Wilkins; 1995. p. 145-50.
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- Carter AO, Elzubeir M, Abdulrazzaq YM, Revel AD, Townsend A. Health and lifestyle needs assessment of medical students in the United Arab Emirates. Med Teach 2003; 25(5): 492-6.
- Oksuz E, Malhan S. Socioeconomic factor and health risk behavior among university students in Turkey: questionnaire study. Croat Med J 2005; 46(1): 66-73.
- Enzyme Immobilization: A Bridge of Understanding between Biotechnology and Pharmacy
Abstract Views :499 |
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Authors
Nisha Nair
1,
Amrita Thakur
1,
Mukta Agrawal
1,
Juhi Thakur
1,
Shubhangi Gupta
1,
Bharti Sahu
1,
Devendra Kumar
1,
Indu Rai
1,
Jaya Sonkar
1,
Kalyani Sahu
1,
Kuldeep
1,
Kailash Kumar
1,
Muktanand
1,
Nidhi Kaushik
1,
Omkar Sahu
1,
Somsunder Sahu
1,
Umesh Kumar
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 109-113Abstract
As the demands of world biotechnology and pharmaceutical industries have increased, a need to develop and enhance, reaction stability, reusability and shelf life of enzymes has also become necessary. Hence noveltechnologies are needed to facilitate large-scale and economic formulations. Enzyme immobilization is a technique most apt to meet all the challenges in regards to enzyme activity. It provides immensescope for increasing availability of enzyme to the substrate and also increases product turn over, also increases the efficiency of an enzyme to a great extent. Immobilization of enzyme can be done by entrapment, support binding, cross-linking of enzyme crystals, etc. For immobilization, numerous natural and synthetic support materials are used. Nowadays, immobilized enzymes are much more preferred rather than their free counterpart because of their prolonged availability. Immobilized enzymesare widely used in pharmaceutical industries, cosmetic industries, food processing, biofuel production and many other sectors. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the current subject.Keywords
Immobilization, Adsorption, Cross-Linking, Microencapsulation, Covalent Bonding.References
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- Kulkarni SJ. Enzyme immobilization: research and studies. Int J Res Rev. 2016; 3(7): 31-35.
- Aehle, W. Enzymes in Industry (Third edition), 2007 Wiley-VCH, ISBN 978-3-527-31689-2, Weinheim
- Literature Survey Methods in Biotechnology: Immobilization of Enzymes and Cells, 2006, 2nd (Ed.), 15-30.
- Costa, S. A.; Azevedo, H. S. and Reis, R. L. Enzymeimmobilization in biodegradable polymers for biomedical applications, In:Biodegradable systemsin tissue engineering and regenerative medicine. R.L. Reis and J. S. Román, (Ed.), 2005, CRC PressLLC, ISBN 978- 0-203-49123-2, London
- Guisan, J. M. Immobilization of enzymes as the 21st century begins, In: Immobilization of enzymesand cells. (Second edition), J. M. Guisan, (Ed.), 2009 Humana Press Inc., ISBN 1-597450537, New Jersey
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- Cao, L. Carrier-bound immobilized enzymes, Principles, Application and Design (first edition), 2005, Wiley-VCH, ISBN 978-1-61583-208-8, Weinheim
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- Formulation Aspects Behind the Development of a Stable Biphasic Liquid Dosage Form with Special Reference to Microemulsion: A Review
Abstract Views :529 |
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Authors
Amrita Thakur
1,
Nisha Nair
1,
Mukta Agrawal
1,
Yashi Thakur
1,
Juhi Thakur
1,
Teman Nirmalkar
1,
Ved Prakash Verma
1,
Vibhash Gupta
1,
Vivek Singh Yadav
1,
Kalpana Mahilange
1,
Pooja Mahant
1,
Pritam Yadav
1,
Deepak Patel
1,
Dinesh Khamari
1,
Jyotsana Meshram
1,
Rakesh Sahu
1,
Tarun Ghatode
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 114-118Abstract
A plethora of research and industrial processes used microemulsion system after its discovery by Jack H. Shulman. The microemulsionis defined as clear, stable, isotropic mixtures of oil, water, and surfactant, frequently in combination with a co-surfactant. They are solutions of oil, water,andamphiphile which are optically isotropic and thermodynamically stable. The aqueous phase present in the system contains salt(s) and other ingredients while the "oil" phase mainly forms a complex of different hydrocarbons and olefins. They do not require high shear conditions as compared to ordinary emulsions. Hence they are easy to prepare. Ultralow interfacial tension, large interfacial area, thermodynamic stability and the ability to solubilize immiscible liquids are some of its unique properties. They also show the ability to protect labile drug, control drug release, increase drug solubility, increase bioavailability and reduce patient variability. Hence, microemulsion has gained most significance in both basictypes of research as well as in industry. They have wide applications and uses such as in pharmaceuticals, cosmetics, cutting oils, biotechnology, food, agrochemicals, environmental detoxification, analytical applications, microporous media synthesis, etc. The microemulsion can be effectively used in dermal delivery because of its mechanism, hence can be used in pharmaceutical and cosmetics preparation. Microemulsion enhances the dermal absorption as they allow rapid penetration of active molecules due to the large surface area of the internal phase and their components reduce the barrier of stratum corneum. Thus, microemulsionisa promising vehicle for effective drug delivery. The current review article deals with information about the microemulsion. Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Microemulsion, Thermodynamically Stable, Bioavailability.References
- T.P. Hoar and J.H. Schulman. Transparent water-in-oil dispersions, the oleopathic hydro micelle. Nature 1943; 152: 102-103.
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- Venkatesh Gavini, M. Srinivasa Murthy, P. Kiran Kumar. Formulation and Invitro Evaluation of Nanoparticulate Drug Delivery System Loaded With 5-Fluorouracil. Res. J. Pharm. Dosage Form. and Tech. 6(4):Oct-Dec.2014; Page 243-248.
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- A Review on Biocompatible Hydrogel: Formulation Aspect and Evaluation
Abstract Views :567 |
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Authors
Shubham Tripathi
1,
Somnath Patel
1,
Ritesh Patel
1,
Shraddha
1,
Pushpendra
1,
Sachin
1,
Neetish
1,
Mahendra
1,
Kuldeep
1,
Prashant
1,
Rajesh Patel
1,
Girish
1,
Nitin
1,
Tomanlal
1,
Amrita Thakur
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 119-122Abstract
Many predefined ways are now a day adopted to interface with biological tissues. One such significant class of biomaterials are hydrogels, which are defined as highly hydrated materials. Hydrogels are designed to absorb a large amount of water or biological fluids due to its three-dimensional, hydrophilic, polymeric network. They closely simulate natural living tissue, more so than any other class of synthetic biomaterials because of their high-water content, porosity,and soft consistency.They are chemically stable but may degrade and gradually disintegrate up to dissolve. Now a day they become more popular because of their unique property of flexibility and biocompatibility. Hydrogels can be produced by both natural and synthetic polymers. These polymers undergo physical and chemical cross-linking to produce hydrogels. Due to their resemblance to the living tissue, they have the immense possibility to use hydrogels in the biomedical field. Some of the well-known use of hydrogels include manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery system and wound dressings. The current review article deals with information about the hydrogels, their various types, preparation methods along with an evaluation of the same.Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Hydrogel, Polymeric Network, Porosity, Biocompatibility, Biomedical.References
- Caló E, Khutoryanskiy VV.Biomedical Applications Of Hydrogels: A Review Of Patents And Commercial Products, European Polymer Journal. 2015; 65: 252-267.
- Das N. Preparation Methods And Properties Of Hydrogels: A Review. International Journal of Pharmacy and Pharmaceutical Sciences. 2013; 5(3): 112-117.
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- Formulation and Characterization of Virgin Coconut Oil Emulsion (VCOE) for Treatment of Alzheimer’s Disease
Abstract Views :579 |
PDF Views:0
Authors
Shubham Tripathi
1,
Umesh Kumar Sahu
1,
Jyotsana Meshram
1,
Ranjeeta Kumari
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1,
Harish Sharma
2,
Gyanesh Kumar Sahu
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka Kurud Road, Bhilai, IN
2 Shri Shankaracharya technical campus, Shri Shankaracharya group of institution, Faculty of Pharmacy, Junwani, Bhilai, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka Kurud Road, Bhilai, IN
2 Shri Shankaracharya technical campus, Shri Shankaracharya group of institution, Faculty of Pharmacy, Junwani, Bhilai, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 49-54Abstract
Alzheimer’s disease, is a somatic disease that affects the brain. It is a progressive disease that destroys memory and other important mental functions. During this disease, accumulation of cerebral extracellular amyloid, which is mostly composed of accumulated amyloid-β (Ab) peptide as well as the accumulation of intracellular neurofibrillary tangles, appears to start up. This results in the loss of connection between nerve cell, and lead to the degeneration of neurons and finally death of brain tissue. Also due to the deficiency of some important chemical messenger in the brain, the signal transmission gets ultimately, affected in the body. The main objective of this study was to prepare the optimized formula of a VCO based emulsion containing Tween 20 as the surfactant for treatment of Alzheimer’s disease which may help to increase the cholesterol level in the brain and to destroy the β amyloid plaque as a result of which the level of chemical messenger will increase in the brain. This study is further aimed to analyze, concentration of drug reaching into the brain and to study its effect in destroying β amyloid plaque.Keywords
Amyloid-β, Chemical Messengers, Neurofibrillary, Tangles, Peptide, Cholesterol.References
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- Pharmaceutical Aspects on the Formulations of Hydrogel: An Update
Abstract Views :483 |
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Authors
Ayushmaan Roy
1,
Anjali Wahane
1,
Siddharth Karankal
1,
Prachi Sharma
1,
Davesh Khutel
1,
Onkarnath Singh
1,
Vinay Shardul
1,
Pitamber
1,
Nausheen Sabha
1,
Jyoti Dewangan
1,
Ajay Dewangan
1,
Akash Jangde
1,
Chaya Rani
1,
Tekeshwar Sahu
1,
D. K. Tripathi
1,
Mukta Agrawal
1,
Ajazuddin
1,
Gyanesh Sahu
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 79-84Abstract
Hydrogels belongs to the classes of 3-dimensional cross-related polymer's community which could withstand the wide varieties of environmental fluctuations. These biomaterials can include massive quantum of biological fluids with extraordinaryswelling properties. whilst swelled, they exhibit opportune biocompatibility. Nowadays drug delivery enjoys several demanding situations where hydrogel might be onedeserving answer to those. Thanks to the specific properties of hydrogel for which they're employed except ionally in the field of biomedical sciences. For this reason, the raining techniques of hydrogel biomaterial and the evaluation of the different classes of above mentioned are most importance. literature's survey suggested that this 3-dimensional structure may be homo-polymeric, co-polymeric, andinterpenetrating polymer networks (IPN) based on guidance techniques. Polymericblends like semi-IPN have additionally been investigated to meet the precise requirements of biomedical science. Particularly emphasizing on biocompatibility, However, bendy strategies of synthesis and tailor in a posit ion physical residencehad made the hydrogels to be used as a drug transport tool in issue engineering. As scaffolds, they also offer structural integrity like tissues regeneration andrepair and as a drug carrier it must have enough mechanical strength to maintain the structural integrity of drug moiety. In this review article a comprehensiveapproach has been made to describe the strategies of hydrogel synthesis withtheir inevitable properties.the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Hydrogel, Homo-polymer, Co-Polymer, Interpenetrating Network, Swelling, Mechanical, Biocompatible.References
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- A Comprehensive Note on Gastro-Retentive Dosage Forms
Abstract Views :583 |
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Authors
Priya Patel
1,
Rohini Sahu
1,
Renjil Joshi
1,
Surabhi Armarkar
1,
Tarannum Parveen
1,
Narendra Pratap
1,
Renuka Sahu
1,
Pushpanjali Sahu
1,
Dujram Sahu
1,
Rupali Manikpuri
1,
Madhav Patel
1,
Tikeshwar Sahu
1,
Bhupendra Rajak
1,
Parmanand Sahu
1,
Pooja Yadav
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 85-89Abstract
Controlled release drug delivery system has achieved greater importance in the field of pharmaceutical sciences to provide therapeutic advantages over the conventional drug delivery system. Nowadays, the gastrointestinal controlled drug delivery system is more prominent than the controlled release system because these can govern the release rate of therapeutically active drug for a sustained period. A Gastro retentive dosage form improves the therapy by prolonging the gastric residence time of the drugs. Prolonged gastric retention improves bioavailability, reduces drug waste and improves solubility for drugs that are less soluble in a high pH environment.In this review, we have discussed various systems associated with gastro retentive drug delivery with their effective mode of action. Also, the approaches and factors to increase the gastric retention time have also been discussed. This drug delivery system has potential to overcome the limitations of the conventional system. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Gastro-Retentive, Controlled Drug Delivery, Floating Drug Delivery, Mucoadhesion.References
- Jain N.K, "Advances in Controlled & Novel Drug Delivery," CBS Publishers & Distributers, New Delhi, Pg 76-95
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- Khan AZ, Tripathi R, Mishra B. Floating elementary osmotic pump tablet for controlled d delivery of diethylcarbamazine citrate: a water- soluble drug. AAPS Pharm Sci Tech, 2011;12(4):1312-1323.
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- A Short Review on the Formulation of Transdermal Dermal Drug Delivery System (TDDS)
Abstract Views :516 |
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Authors
Alok Ranjan
1,
Aishwarya Sahu
1,
Akansha Yadav
1,
Alka Payasi
1,
Akash Jaiswal
1,
Akshay Kumar
1,
Akash Sahu
1,
Ashwani Jangde
1,
Chandrashekhar Nayak
1,
Dev Kumar
1,
Harshita Yarda
1,
Mitali Sahu
1,
Nokesh Sahu
1,
Rajesh Patel
1,
Nisha Nair
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 90-94Abstract
The transdermal drug delivery systems (TDDS) are drug delivery system that gives rapid, the immediate therapeutic effect of the drug across the patient’s skin and its different layers. They are also called as patches. More than 75% of the drugs, now a day’s, are taken orally and are not very much effective. To overcome these problems, the transdermal drug delivery system has been evolved. The advantage of transdermal patches is that they deliver the drugs for better systemic effects at a controlled and a predetermined rate. This drug delivery system also endorses the controlled release of drug medicament into the skin of the patients. The chief aim of this drug delivery system is to deliver the drug contents into the systemic circulation through the permeation of skin at a predetermined rate. This article is an overview of different types of transdermal patches, their various method of preparation as well as their various physicochemical evaluation methods. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
TDDS, Systemic Circulation, Transdermal Patches, Systemic Effects, Drug Medicament, Novel Drug Delivery System.References
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- Hafeez, A Recent Advances in Transdermal Drug Delivery System (TDDS): An Overview, Journal of Scientific and Innovative Research. 2013; 2(3): 733-744.
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- Self Microemulsifying Drug Delivery System (SMEDDS): A Novel Approach to Improve the Therapeutic Efficacy of Orally Administered Drug
Abstract Views :570 |
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Authors
Kritika Kanoujia
1,
Chandraprabha Dewangan
1,
AyushI Masih
1,
Dipti Sinha
1,
Divya Oraon
1,
Manisha Jaiswal
1,
Monika Sahu
1,
Ranjeeta Kumari
1,
Sapna Pradhan
1,
Ravi Suman
1,
Rajkishan Dewangan
1,
Roman Banjare
1,
Pradeep Paikra
1,
Mukesh Rawtiya
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 95-102Abstract
The oral route is most preferred one as there is ease of administration and it is a painless approach. This favored route is restricted to those drug molecules that are absorbent over gastric mucosa. One of the promising techniques is SMEDDS. Self-micro emulsifying drug delivery system has gained more attention due to enhanced oral bioavailability enabling a reduction in dose, more consistent temporal profiles of drug absorption, selective targeting of drug towards specific absorption window in GIT, and protection of drugs from the unreceptive environment in the gut. SMEDDS provide the dissolved drugs form,and also its small size of droplets imparts substantial interfacial area for the absorption of drugs. It can simply get penetrated into the GIT which is the major advantages over another emulsion. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
SMEDDS, Oral Drug Delivery, GIT, Solubility, Bioavailability.References
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- Understanding the Concept of Mucoadhesive Drug Delivery System: A Novel Approach over Conventional Dosage Forms
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Authors
Umesh Kumar
1,
Khuman Lal
1,
Navneet Patel
1,
Lekhraj
1,
Jai Prakash
1,
Omkar
1,
Rakesh Gurjar
1,
Achyutanand Gupta
1,
Chandra Prakash
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 103-108Abstract
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for the improved therapeutic outcome. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. The mucoadhesive ability of a dosage form is dependent upon a variety of factors, including the nature of the mucosal tissue and the physicochemical properties of the polymeric formulation. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Mucoadhesion, Mucoadhesive System, Bioadhesion, Transmucosal, Transdermal, Bioavailability.References
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