Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

A Review on Biocompatible Hydrogel: Formulation Aspect and Evaluation


Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
     

   Subscribe/Renew Journal


Many predefined ways are now a day adopted to interface with biological tissues. One such significant class of biomaterials are hydrogels, which are defined as highly hydrated materials. Hydrogels are designed to absorb a large amount of water or biological fluids due to its three-dimensional, hydrophilic, polymeric network. They closely simulate natural living tissue, more so than any other class of synthetic biomaterials because of their high-water content, porosity,and soft consistency.They are chemically stable but may degrade and gradually disintegrate up to dissolve. Now a day they become more popular because of their unique property of flexibility and biocompatibility. Hydrogels can be produced by both natural and synthetic polymers. These polymers undergo physical and chemical cross-linking to produce hydrogels. Due to their resemblance to the living tissue, they have the immense possibility to use hydrogels in the biomedical field. Some of the well-known use of hydrogels include manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery system and wound dressings. The current review article deals with information about the hydrogels, their various types, preparation methods along with an evaluation of the same.Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.

Keywords

Hydrogel, Polymeric Network, Porosity, Biocompatibility, Biomedical.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Caló E, Khutoryanskiy VV.Biomedical Applications Of Hydrogels: A Review Of Patents And Commercial Products, European Polymer Journal. 2015; 65: 252-267.
  • Das N. Preparation Methods And Properties Of Hydrogels: A Review. International Journal of Pharmacy and Pharmaceutical Sciences. 2013; 5(3): 112-117.
  • Hoare TR, Kohane DS. Hydrogels In Drug Delivery: Progress And Challenges. Polymer. 2008; 49(8): 1993-2007.
  • Phadke A, Zhang C, Arman B, ChengChih Hsu, Mashelkar R. Lele A, Tauber M, Arya G,andVarghese S.Rapid Self-Healing Hydrogels.Proceedings of the National Academy of Sciences. 2012; 109: 4383-4388.
  • Dwivedi S, Khatri P, Mehra GR,Kumar V. Hydrogel-A Conceptual Overview. International Journal of Pharmaceutical and Biological Archives. 2011; 2(6): 1588-1597.
  • Ahmed EM. Hydrogel: Preparation, Characterization And Applications. Journal of advanced research. 2015; 6(2): 105-121.
  • Iizawa T, Taketa H, Maruta M, Ishido T, Gotoh T, Sakohara S. Synthesis of porous poly (N-isopropylacrylamide) gel beads by sedimentation polymerization and their morphology. Journal of applied polymer. 2007; 104: 842-850.
  • Singh SK, Dhyani A,Juyal D. Hydrogel: Preparation, Characterization And Applications. The Pharma Innovation Journal. 2017; 6(6): 25-32.
  • Himi M, Maurya SD, Preparation and Evaluation Of Stomach Specific IPN Hydrogels For Oral Drug Delivery: A Review. Journal of Drug Delivery and Therapeutics. 2013, 3(2), 131-140.
  • Swarbrick J, Encyclopedia Of Pharmaceutics, 4th edition,Vol III, F-O, 6000 Broken Sound Parkway NW, Suite300, Boca Raton, FL 33487-2742, Taylor and Francis Group,, 2013.
  • Bindu M, Ashok. V, Chatterjee A. Review Article As A Review On Hydrogels As Drug Delivery In The Pharmaceutical Field. International Journal of pharm and chemical sciences ISSN: 2277: 5005: 642-661.
  • Aulton M., Aulton’s pharmaceutics, The Design and Manufacture of Medicines, Third Edition, Elsevier’s Health Sciences Rights Department, 1600 John F. Kennedy Boulevard, Suite 1800, Philadelphia, PA 19103-2899, Harcourt Publishers Limited 2001.
  • Chien Y. Novel drug delivery systems. second edition, New York, 52 Vanderbuilt Avenue, Informa Healthcare USA, Inc, 2009.

Abstract Views: 1

PDF Views: 0




  • A Review on Biocompatible Hydrogel: Formulation Aspect and Evaluation

Abstract Views: 1  |  PDF Views: 0

Authors

Shubham Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Somnath Patel
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Ritesh Patel
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Shraddha
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Pushpendra
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Sachin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Neetish
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Mahendra
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Kuldeep
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Prashant
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Rajesh Patel
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Girish
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Nitin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Tomanlal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Amrita Thakur
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Mukta Agrawal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Ajazuddin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
D. K. Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Amit Alexander
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India

Abstract


Many predefined ways are now a day adopted to interface with biological tissues. One such significant class of biomaterials are hydrogels, which are defined as highly hydrated materials. Hydrogels are designed to absorb a large amount of water or biological fluids due to its three-dimensional, hydrophilic, polymeric network. They closely simulate natural living tissue, more so than any other class of synthetic biomaterials because of their high-water content, porosity,and soft consistency.They are chemically stable but may degrade and gradually disintegrate up to dissolve. Now a day they become more popular because of their unique property of flexibility and biocompatibility. Hydrogels can be produced by both natural and synthetic polymers. These polymers undergo physical and chemical cross-linking to produce hydrogels. Due to their resemblance to the living tissue, they have the immense possibility to use hydrogels in the biomedical field. Some of the well-known use of hydrogels include manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery system and wound dressings. The current review article deals with information about the hydrogels, their various types, preparation methods along with an evaluation of the same.Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.

Keywords


Hydrogel, Polymeric Network, Porosity, Biocompatibility, Biomedical.

References