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Enzyme Immobilization: A Bridge of Understanding between Biotechnology and Pharmacy


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1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
     

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As the demands of world biotechnology and pharmaceutical industries have increased, a need to develop and enhance, reaction stability, reusability and shelf life of enzymes has also become necessary. Hence noveltechnologies are needed to facilitate large-scale and economic formulations. Enzyme immobilization is a technique most apt to meet all the challenges in regards to enzyme activity. It provides immensescope for increasing availability of enzyme to the substrate and also increases product turn over, also increases the efficiency of an enzyme to a great extent. Immobilization of enzyme can be done by entrapment, support binding, cross-linking of enzyme crystals, etc. For immobilization, numerous natural and synthetic support materials are used. Nowadays, immobilized enzymes are much more preferred rather than their free counterpart because of their prolonged availability. Immobilized enzymesare widely used in pharmaceutical industries, cosmetic industries, food processing, biofuel production and many other sectors. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the current subject.

Keywords

Immobilization, Adsorption, Cross-Linking, Microencapsulation, Covalent Bonding.
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  • Enzyme Immobilization: A Bridge of Understanding between Biotechnology and Pharmacy

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Authors

Nisha Nair
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Amrita Thakur
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Mukta Agrawal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Juhi Thakur
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Shubhangi Gupta
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Bharti Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Devendra Kumar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Indu Rai
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Jaya Sonkar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Kalyani Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Kuldeep
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Kailash Kumar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Muktanand
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Nidhi Kaushik
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Omkar Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Somsunder Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Umesh Kumar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
D. K. Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Ajazuddin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India
Amit Alexander
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, India

Abstract


As the demands of world biotechnology and pharmaceutical industries have increased, a need to develop and enhance, reaction stability, reusability and shelf life of enzymes has also become necessary. Hence noveltechnologies are needed to facilitate large-scale and economic formulations. Enzyme immobilization is a technique most apt to meet all the challenges in regards to enzyme activity. It provides immensescope for increasing availability of enzyme to the substrate and also increases product turn over, also increases the efficiency of an enzyme to a great extent. Immobilization of enzyme can be done by entrapment, support binding, cross-linking of enzyme crystals, etc. For immobilization, numerous natural and synthetic support materials are used. Nowadays, immobilized enzymes are much more preferred rather than their free counterpart because of their prolonged availability. Immobilized enzymesare widely used in pharmaceutical industries, cosmetic industries, food processing, biofuel production and many other sectors. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the current subject.

Keywords


Immobilization, Adsorption, Cross-Linking, Microencapsulation, Covalent Bonding.

References