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Clinico-Pathological Study of Cervical Lymphadenopathy in a Tertiary Care Centre
Introduction: Cervical lymphadenopathy is common in India and may present as diagnostic problem to the clinician. Diseases affecting cervical lymph nodes are of varying severity starting from simple curable infection to difficult incurable malignant disease. Objective: The purpose of this study was to observe the various clinical presentations of cervical lymphadenopathy and correlate histopathological findings with the clinical diagnosis. Methods: A cross sectional study was conducted during the period from August 2015 to December 2017 at a tertiary care centre on 50 patients presenting with cervical lymphadenopathy. Results: In this series, tissue diagnosis by biopsy found Tuberculosis (TB) 74% cases, metastatic carcinoma in 12%, and non-specific reactive hyperplasia in 10% and lymphoma in 4% cases. Seventy six percent cases were below 40 years of age. Conclusion: Thirty-Seven (74%) cases were diagnosed clinically as tubercular lymphadenitis, 05(10%) as metastatic carcinoma, 06(12%) non-specific reactive hyperplasia and 02(4%) cases were of lymphoma which was nearly similar to histopathological diagnosis.
Biopsy, Cervical Lymphadenopathy, Fine Needle Aspiration Cytology (FNAC), Non-Specific Reactive Hyperplasia, Tubercular Lymphadenitis.
- Gosche JR, Vick L. Acute, subacute, and Chronic Cervical Lymphadenitis in children, Semin. Pediatr. Surg. 2006; 15:99-106. https://doi.org/10.1053/j.sempedsurg. 2006.02.007. PMid: 16616313.
- Bradbury AW. «Lymphedema» in Bailey and Love’s Short Practice of Surgery, 24th Edition Arnold, 2004; 974p.
- Bhatt JV, Shah JM, Shah F. Clinico-pathological profile of cervical lymphadenopathy: A prospective study, J. Appl. Basic. Med. Sci. 2002; 2(2):35-39 http://www.nhlmmcgym.com/clinico- pathological-profile-cervical.htm.
- Fijten GH, Blijham GH. Unexplained lymphadenopathy in family practice. An evaluation of the probability of malignant causes and the effectiveness of physicians’ workup, J. Fam. Pract. 1988; 27:373-76.
- Buli G, Lukas F. Cytologic patterns of lymph node diseases in Hawassa University Referral Hospital, Southern Ethiopia, Journal of Coastal Life Medicine. 2015; 3:395-97. https://doi.org/10.12980/JCLM.3.2015JCLM-2015-0024.
- Shaikh SM, Balochi I, Bhatti Y, Shah AA, Shaikh GS, Deenari RA. An audit of 200 cases of cervical lymphadenopathy, Med. Channel. 2010; 16(1):85-87.
- Mukherjee AK. Tuberculosis control programme in India: Progress and prospects, Indian J. Tuberc. 1995; 42:75-85.
- Hooper AA. Tuberculous peripheral lymphadenitis, Br. J. Surg. 1972; 59:353-9. https://doi.org/10.1002/bjs.1800590506. PMid: 5021137.
- Parisi E, Glick M, Cervical lymphadenopathy in the dental patient: A review of clinical approach, Quintessence Int. 2005; 36(6):423-426.
- Shakya G, Malla S, Shakya KN, Shrestha R. A study of FNAC of cervical lymph nodes, J. Nepal Health Res. Counc. 2009; 7(14):1-5. https://doi.org/10.3126/jnhrc.v7i1.2267.
- Larsson LO, Bentzon MW, Berg K, Mellander L, Skoogh BE, Stranegård IL. Palpable lymph nodes of the neck in Swedish schoolchildren, Acta. Paediatrica. 1994; 83,1092-94. https://doi.org/10.1111/j.1651-2227.1994.tb12992.x. PMid:7841711.
- Andrew Coughlin, Shraddha S Mukerji. Pediatric_Cervical_Lymphadenopathy. Grand Rounds Presentation, The University of Texas Medical Branch, Department of Otolaryngology, Sep 2019. https://www.researchgate.net/publication/267551437_Pediatric_ Cervical_Lymphadenopathy
- Cummings: Otolaryngology: Head and Neck Surgery, 4th ed.
- Narang RK, Pradhan S, Singh RP, Chaturvedi S. Place of fine needle aspiration cytology in the diagnosis of lymphadenopathy, Ind. J. Tub. 1990; 37:29-31.
- Khan RA, Wahab S, Chana RS, Naseem S, Siddique S. Children with significant cervical lymphadenopathy: Clinico- pathological analysis and role of fine-needle aspiration in Indian setup, J. Pediatr. 2008; 84(5):449-54. https://doi.org/10.2223/JPED.1840. PMid: 18923792.
- Khajuria R, Goswami KC, Singh K, Dubey VK. Pattern of lymphadenopathy on FNAC in Jammu, JK Science. 2006; 8(3):157-9.
- Biswas G, Das A, Haldar D, Mukherjee A, Dutta S, Sinha R. Clinico-pathological correlates of cervical lymphadenopathy: A hospital based study, Indian Journal of Otolaryngology and Head and Neck Surgery. 2013 Jul 1; 65(1):42-7. https://doi.org/10.1007/s12070-011-0443-z. PMid:24427614, PMCid:PMC3718945.
- Morland B. Lymphadenopathy, Arch. Dis. Child. 1995; 73:476-79. https://doi.org/10.1136/adc.73.5.476. PMid:8554372, PMCid:PMC1511364.
- Pangalis GA, Vassilakopoulos TP, Boussiotis VA, Fessas P. Clinical approach to lymphadenopathy, Semin. Oncol. 1993; 20:570-82.
- McHenry CR, Cooney MM, Slusarczyk SJ, Khiyami A, A Supraclavicular lymphadenopathy: The spectrum of pathology and evaluation by fine needle aspiration biopsy, Am. Surgery. 1999; 65:742-46.
- Choi P, Qin X, Chen EY, Inglis AF Jr, Ou HC, Perkins JA, Sie KC, Patterson K, Berry S, Manning SC. Poly- merase chain reaction for pathogen identification in persistent pediatric cervical lymphadenitis, Arch. Oto-laryngol Head Neck Surg. 2009; 135:243-48. https://doi.org/10.1001/archoto.2009.1. PMid:19289701.
- Vincet C, Cervical lymphadenopathy: What radiologists need to know, Cancer Imaging. 2004; (4):116-20. https://doi.org/10.1102/1470-7330.2004.0020. PMid: 18250018, PMCid: PMC1434593.
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