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The Study of Clinical Profile, Risk Factors, Management and Outcome of Acute Myocardial Infarction in Women Admitted at Tertiary Care Teaching Hospital
Aims and Objectives: To study the clinical profile, risk factors, management and outcome of Acute Myocardial Infarction (AMI) in women admitted at Tertiary Care Hospital. Materials and Methods: It was a prospective observational study. After obtaining permission from the Institutional Ethics committee this study was carried out. 80 women with acute myocardial infarction admitted at tertiary health care center during a period of two years were recruited for the study. The data, consisting of detailed history, clinical features, risk factors, relevant investigations, management, course in the hospital and ultimate outcome was obtained and documented in a tabulated format. This data was carefully studied and statistically analyzed by applying appropriate statistical tests and inferences were drawn. Results: Study showed maximum number of women admitted with acute myocardial infarction (37.50%), were elderly, belonging to the age group of 61 to 70. Majority of the women (75%) were multiparous as compared to primiparous. Majority of these women also were postmenopausal (87.5%) as compared to premenopausal. 54 women (67.5%) presented to the hospital in less than 12 hours of onset of symptoms, out of it which 52(96.29%) women survived and 2(3.71%) died. 26 women (32.5%) presented to the hospital after the 12 hours of onset of symptoms, out of it 16 women (61.53%) survived and 10 succumbed (38.4%). Conclusion: The survival rate was higher when the time lag between onset of symptoms and starting the treatment was ≤12 hours.
Acute Myocardial Infarction, Outcome, Risk Factors, Women.
- Lloyd-Jones D, Adams R, Carnethon M, De Simone G, et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. 2009 Jan 27; 119(3):e21181. doi:10.1161/CIRCULATIONAHA. https://www.ncbi.nlm.nih.gov/pubmed/19075105.
- Kim ESH, Carrigan TP, Menon V. Enrollment of Women in National Heart, Lung, and Blood Institute - Funded Cardiovascular Randomized Controlled Trials Fails to Meet Current Federal Mandates for Inclusion, J. Am. Coll. Cardiol. 2008; 52(8):672-73. https://doi.org/10.1016/j.jacc.2008.05.025. PMid:18702973.
- Pepine CJ. Ischemic Heart Disease in Women, J. Am. Coll. Cardiol. 2006; 47:S1-S3. https://doi.org/10.1016/j.jacc.2005.10.022.PMid:16458166.
- Mikhail GW. Coronary Heart Disease in Women, BMJ. 2005; 331(7515):467-68. https://doi.org/10.1136/bmj.331.7515.467. PMid:16141136, PMCid:PMC1199011.
- Wenger NK. Coronary Heart Disease: The Female Heart is Vulnerable, Prog. Cardiovasc. Dis. 2003; 46(3): 199-299. https://doi.org/10.1016/j.pcad.2003.08.003. PMid: 14685940.
- Stampfer MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE, et al. Postmenopausal Estrogen Therapy and Cardiovascular Disease. N. Engal. J. Med. 1991; 325:756-62. https://doi.org/10.1056/NEJM199109123251102. PMid: 1870648.
- Stamfer MJ, Colditz GA. Estrogen Replacement Therapy and Coronary Heart Disease: Quantitative Assessment of the Epidemiologic Evidence, Prev. Med., 1991; 20(1):47-63. https://doi.org/10.1016/0091-7435(91)90006-P.
- Shruthi Bettegowda. Clinical Profile of Ischemic Heart Disease in Women with Special Reference to the Risk, Sch. J. App. Med. Sci., 2014; 2(6C):3020-25. ISSN 2320-6691 (Online).
- Manish Sahni, Rajesh Kumar, Surinder Thakur, Rajeev Bhardwaj. Clinical Profile, Risk Factors and Short Term Outcome of Acute Myocardial Infraction in Females: A Hospital Based Study, Heart India. Oct-Dec 2013; 1(3):73-77. https://doi.org/10.4103/2321-449X.122780.
- Veena Nanjappa, Gopi Aniyathodiyil R, Keshava. Clinical Profile and 30-Day Outcome of Women with Acute Coronary Syndrome as a First Manifestation of Ischemic Heart Disease: A Single-Center Observational Study, Indian Heart Journal. 2016; 68:164-68. https://doi.org/10.1016/j.ihj.2015.08.006. PMid: 27133325, PMCid: PMC4867941.
- David A. Alter, David Naylor C, Peter Austin, Jack V Tu. Effects of Socioeconomic Status on Access to Invasive Cardiac Procedures and on Mortality after Acute Myocardial Infarction, N. Engl. J. Med. 1999; 341:1359-67. DOI: https://doi.org/10.1056/NEJM199910283411806. PMid: 10536129.
- Bea C Tanis, Maurice AAJ, van den Bosch, Jeanet M Kemmeren, Volkert Manger Cats, Frans M Helmerhorst, Ale Algra, Yolanda van der Graaf, Frits R. Rosendaal. Oral Contraceptives and the Risk of Myocardial Infarction, N. Engl. J. Med. 2001; 345:1787-93. doi: https://doi.org/10.1056/NEJMoa003216. PMid: 11752354
- Dave TH, Wasir HS, Prabhakaran D, Dev V, Das G, Rajani M, Venugopal P, Tandon R. Profile of Coronary Artery Disease in Indian Women: Correlation of Clinical, Non Invasive and Coronary Angiographic Findings, Indian Heart J. 1991 Jan-Feb; 43(1):25-29.
- Sree Ranga PC, Kumar Swamy V, Veeranna Gowda, Devadass PK, Manjunaths CN. Angiographic Pattern of Coronary Artery Disease in Women, International Journal of Recent Trends in Science and Technology. October 2015; 16(3):54244. Accessed 12 October 2015. http://www.statperson.com.
- Gilles Montalescot, Jean Dallongeville, Eric Van Belle, Stephanie Rouanet, Cathrine Baulac, Alexia Degrandsart, Eric Vicaut, for the OPERA Investigators. STEMI and NSTEMI: Are they so Different 1 Year Outcomes in Acute Myocardial Infarction as Defined by the ESC/ACC Definition (the OPERA registry), European Heart Journal. 1 June 2007; 28(12):1409-17. https://doi.org/10.1093/eurheartj/ ehm031. PMid: 17412730
- Vaccarino V, Parsons L, Every NR, Barron HV, Krumholz HM. Sex-Based Differences in Early Mortality after Myocardial Infarction, N. Engl. J. Med. 1999; 341:217-25. https://doi.org/10.1056/NEJM199907223410401. PMid: 10413733.
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