Open Access Subscription Access
Study of Drug Utilization Pattern in Acne Vulgaris in Skin Outpatient Department in Tertiary Health Care Centre
Background: Acne vulgaris is common skin disorder which dermatologists come across in day to day practice. Drug utilization studies are very useful to explore role of drugs in the society. It involves prescription, distribution, marketing and use of drugs and its different consequences like medical and socio-economic. Aims and Objective: To obtain information of drug prescription pattern in acne vulgaris in skin outpatient department and to evaluate pattern of prescription using World Health Organization (WHO) drug use prescribing indicators. Material and Methods: This was cross sectional observational study conducted by department of pharmacology in dermatology OPD in medical college and tertiary care centre from August 2015 to December 2017. During study period total 414 prescriptions of acne patients were analysed. Results: Out of 414 patients 226 (54.59%) were females and 188 (45.41 %) were males with male to female ratio was 1:1.20. Majority of patients belonged to 21-25 years (38.90%) followed by 15-20 (36.48%), 26-30 (18.59%), 31-35 (4.59%) and 36-40 (1.44%) with Mean age of 22.74 years. Grade II (52.66 %) consists of the majority of patients while others Grade I (35.27%), grade III (10.14%) and grade IV (1.93%). Monotherapy was prescribed in 35.26% cases and polytherapy in 64.74% cases. A total number of 950 drugs were prescribed out of them 306 (32.21%) were oral and 644 (67.79%) were topical, percentage of total fixed dose combination of topical preparations were 4%. Average number of drugs per prescription were 2.29. All drugs prescribed by prescribers are in brand names 76% (722 out of 950) of drugs were prescribed from national essential medicines list (NELM, 2015) and 19th WHO list of essential medicines, April 2015. Conclusion: Percentage of drugs prescribed in this study from National List of Essential Medicines (NLEM) was satisfactory but shows complete use of Non-Generic (Branded) drugs. The prescription audit or the drug utilization studies can be used as further basis for the prescribers. Periodic drug audits must be conducted to reduce errors, make prescription rationalize and for effective management of acne vulgaris.
Acne Vulgaris, Drug Utilization Pattern, WHO Drug Prescribing Indicators.
- Ebling FJG, Cunliffe WJ. Disorders of sebaceous glands. In: Rook / Wilkinson/ Ebling, Textbook of dermatology, Fifth edition, vol.4, chapter 38, Willey-Blackwell publication p. 1699-744.
- World health organization, Introduction to drug utilization research, Geneva; 2003, p. 6-48.
- Santosh Kumar, Shaktibala Dutta, Mirza Atif Beg, Anil Kumar Mehta, Mohammad Anjoom, Saubhagya Sindhu. Drug utilization pattern in acne vulgaris in skin outpatient’s department of a tertiary care teaching hospital at Dehradun, Uttarakhand, International Journal of Medical Science and Public Health. 2014; 3(7):855-58.
- WHO, How to investigate drug use in health facilities; selected drug use indicators, Geneva, World health organization 19993; WHO/DAP/93.1.
- Nibedita Patro, MonalisaJenna, Maitreyee Panda, Mrutyunjay Dash. A study on the prescribing pattern of drugs for acne in a tertiary care teaching hospital in Odisha, Journal of CLINICAL and Diagnostic Research. 2015; 9(3): WC04-WC066.
- Santosh Kumar, Shaktibala Dutta, Mirza Asif Beg, Anil Kumar Mehta, Mohammad Anjoom, Saubhagya Sindhu. Drug utilization pattern in acne vulgaris, International Journal of Medical Science and Public Health. 2014; 3:855-58. https://doi.org/10.5455/ijmsph.2014.120420142.
- Vinay Sharma, Anurag Bajpai. Study of prescription pattern for acne vulgaris in dermatology OPD in a tertiary care teaching hospital, International Journal of Medical Research Professionals. 2016; 2(2):316-19.
- Nandini T, Shivprasad K, Padmanabha TS, Purushotham K, Narendra G. A prospective study of pattern of prescription for acne vulgaris in a tertiary care hospital: An observational study, Int. J. Basic and Clin. Pharmacology. 2016; 5(6):2357-61.
- Agrawal Sneha, Pillai Ajit, Singh Anil, Parik Reena, Bhuptani Neeta. Drug utilization study of medications used for acne vulgaris in a tertiary care hospital, EJBPS. 2016; 3,11,311-15.
- National list of essential medicines in India 2015. Accessed on 25 September 2017. www.pharmaceuticals.gov.in/pdf/NLEM.pdf.
Abstract Views: 3
PDF Views: 0