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The Prevalence of Syphilis Infection and Its Associated Factors in the General Population of Rwanda: A National Household-Based Survey


Affiliations
1 Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda
2 Global Evaluative Sciences, Vancouver, BC, Canada
3 Institute of Human Virology and Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, United States
 

Background: The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We conducted this survey in 2013 to estimate the prevalence of syphilis. Methods: A cross-sectional survey. Participants were tested for syphilis and HIV. Factors associated with syphilis infection were identified. Results: The prevalence of syphilis was 0.9% (95% CI: 0.7–1.1). This prevalence was higher in the 25–49-year-old age (1.1% [95% CI: 0.8–1.3]) than in the 15–24-year-old age (0.6% (95% CI: 0.4–0.9)). Women with lower education had a higher prevalence of syphilis (1.2% (95% CI: 0.9–1.5)) compared to others (0.4% (95% CI: 0.2–0.8)). This prevalence among HIV-infected people was six times higher: 4.8% (95% CI: 2.9–7.9) compared to HIV-negative people (0.8% (95% CI: 0.6–1.0)). The prevalence of syphilis among HIV-infected females was 5.9% (95% CI: 3.4–10.0). HIV-infected or concurrent sexual partners was associated with increased syphilis prevalence with aOR = 4.2 (95% CI: 2.5–7.2) and aOR = 4.2 (95% CI: 2.8–6.5), respectively. Conclusions: The prevalence of syphilis was significantly higher among HIV-infected patients. HIV infection and concurrent sexual partners are associated with an increased prevalence of syphilis. Preventing HIV might help in preventing syphilis.
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  • The Prevalence of Syphilis Infection and Its Associated Factors in the General Population of Rwanda: A National Household-Based Survey

Abstract Views: 69  |  PDF Views: 1

Authors

Mwumvaneza Mutagoma
Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda
Eric Remera
Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda
Dieudonne Sebuhoro
Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda
Steve Kanters
Global Evaluative Sciences, Vancouver, BC, Canada
David J. Riedel
Institute of Human Virology and Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, United States
Sabin Nsanzimana
Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda

Abstract


Background: The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We conducted this survey in 2013 to estimate the prevalence of syphilis. Methods: A cross-sectional survey. Participants were tested for syphilis and HIV. Factors associated with syphilis infection were identified. Results: The prevalence of syphilis was 0.9% (95% CI: 0.7–1.1). This prevalence was higher in the 25–49-year-old age (1.1% [95% CI: 0.8–1.3]) than in the 15–24-year-old age (0.6% (95% CI: 0.4–0.9)). Women with lower education had a higher prevalence of syphilis (1.2% (95% CI: 0.9–1.5)) compared to others (0.4% (95% CI: 0.2–0.8)). This prevalence among HIV-infected people was six times higher: 4.8% (95% CI: 2.9–7.9) compared to HIV-negative people (0.8% (95% CI: 0.6–1.0)). The prevalence of syphilis among HIV-infected females was 5.9% (95% CI: 3.4–10.0). HIV-infected or concurrent sexual partners was associated with increased syphilis prevalence with aOR = 4.2 (95% CI: 2.5–7.2) and aOR = 4.2 (95% CI: 2.8–6.5), respectively. Conclusions: The prevalence of syphilis was significantly higher among HIV-infected patients. HIV infection and concurrent sexual partners are associated with an increased prevalence of syphilis. Preventing HIV might help in preventing syphilis.