Journal of Pharmaceutical Research

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Mucoadhesive Polymers:A Review


Affiliations
1 Department of Pharmaceutics, 12/1, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Varthur (H), Bangalore-560035, India
 

Purpose: Aim of the study is to explore the concept of mucoadhesion, theories and the various polymers used in mucoadhesive drug delivery. Approach: An extensive review is carried out on mechanism of mucoadhesion, theories, polymers used in mucoadhesive dosage forms and its applications. Finding: Mucoadhesive polymers increases the residence time, prolongs the absorption, enhances solubility and dissolution characteristics of poorly soluble drugs. Conclusion: Mucoadhesive polymers was found to be a novel drug carrier used in buccal, nasal, vaginal, ocular, rectal drug delivery which improves bioavailability of poorly soluble drugs.

Keywords

Mucoadhesive Polymer, Mucoadhesion, Bioavailability.
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Abstract Views: 416

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  • Mucoadhesive Polymers:A Review

Abstract Views: 416  |  PDF Views: 85

Authors

Anjana Anil
Department of Pharmaceutics, 12/1, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Varthur (H), Bangalore-560035, India
Preethi Sudheer
Department of Pharmaceutics, 12/1, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Varthur (H), Bangalore-560035, India

Abstract


Purpose: Aim of the study is to explore the concept of mucoadhesion, theories and the various polymers used in mucoadhesive drug delivery. Approach: An extensive review is carried out on mechanism of mucoadhesion, theories, polymers used in mucoadhesive dosage forms and its applications. Finding: Mucoadhesive polymers increases the residence time, prolongs the absorption, enhances solubility and dissolution characteristics of poorly soluble drugs. Conclusion: Mucoadhesive polymers was found to be a novel drug carrier used in buccal, nasal, vaginal, ocular, rectal drug delivery which improves bioavailability of poorly soluble drugs.

Keywords


Mucoadhesive Polymer, Mucoadhesion, Bioavailability.

References