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Singh, Anjali
- Di (2-Ethylhexyl) Phthalate Induced Toxicological Effects on Reproductive System of Female Mice Mus-Musculus
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Authors
Affiliations
1 Department of Botany and Biotechnology, Thakur Prasad Singh (T.P.S. College) College, Patliputra University, Patna – 800020, Bihar, IN
2 S. S. Hospital and Research Institute, Patna – 800020, Bihar, IN
1 Department of Botany and Biotechnology, Thakur Prasad Singh (T.P.S. College) College, Patliputra University, Patna – 800020, Bihar, IN
2 S. S. Hospital and Research Institute, Patna – 800020, Bihar, IN
Source
Journal of Ecophysiology and Occupational Health, Vol 19, No 1-2 (2019), Pagination: 71-75Abstract
Di-(2-ethylhexyl) phthalate is an environmental endocrine disruptor and reproductive toxicant. It impairs the structural and functional aspects of female reproduction and also alters the molecular, endocrinological, cytological and biochemical aspects, causing ovarian cycle irregularity and infertility. DEHP was orally administered at lower dose of 10 mg/kg bwt to mice for six to twenty four weeks period which resulted in alterations of the serum levels of hormones estrogen and progesterone. The altered values of hormones were found to be statistically very significant (P<0.001). The present study indicated the adverse effects of exposure of DEHP on female reproductive health.
Keywords
Corn Oil Reproductive System, DEHP, Hormones, Infertility.Full Text
References
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- Biodegradation of Di-(2-Ethylhexyl Phalate) by Bacillus antracis (Accession no. KJ085972.1)
Abstract Views :237 |
PDF Views:99
Authors
Affiliations
1 TPS College, Patna – 800001, Bihar, IN
2 Department of Biotechnology, Magadh University, Bodh Gaya – 824234, Bihar, IN
3 DST-WOS, TPS College, Patna – 800001, Bihar, IN
1 TPS College, Patna – 800001, Bihar, IN
2 Department of Biotechnology, Magadh University, Bodh Gaya – 824234, Bihar, IN
3 DST-WOS, TPS College, Patna – 800001, Bihar, IN
Source
Journal of Ecophysiology and Occupational Health, Vol 20, No 3&4 (2020), Pagination: 140-144Abstract
DEHP is one of the most broadly used PAEs (Phthalic Acid Esters) as a plasticizer in Polyvinyl Chloride (PVC) manufacturing. The DEHP and its other monoester metabolites are considered as very harmful for animal and human and affect the endocrine system. The strain isolated in this study is very efficient in degrading the DEHP. The degrading bacterial strain Bacillus anthracis is used in this study to determine the biological degradation potential of DEHP. Bacteria play very important roles in DEHP degradation in the environment under various conditions. The selected strain in for DEHP degrading bacteria designated as strain T-10 is optimized at the different conditions for its maximum activity at different temperatures, pH, chemicals like carbon and nitrogen source identified with degradation potential of more than 85%.
Keywords
Bacteria, Biodegradation, DEHP, PlasticizerFull Text
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