Lead Exposure on Blood Pressure and Lipid Parameters Alteration among People around Bus Terminal in Yogyakarta
Lead is generated as residual progress of vehicle or factory process. The excessive amount of lead has several impacts on human health system namely on cardiovascular, respiratory, endocrine and metabolic system through damaging enzymatic process and Reactive Oxygen Species (ROS). The aim of this study is to search the correlation of lead exposure on blood pressure and lipid parameters alteration among people around bus terminal in Yogyakarta. This study is a cross sectional research design. According to calculation of sample size, 71 respondents had fulfilled the inclusion criteria such as: Agree to be respondents, 6 hours fasting prior to take data, age >18 years old and had history of staying nearby bus terminal for more than one year. The variables divided into two, independent variable is lead exposure and dependent variables are SBP and DBP meanwhile lipid parameters such as LDL, HDL and TG. Those variables were analyzed by linier regression. Based on linier regression was obtained that SBP (p value 0.004, r 0.33 and R square 0.11), DBP (p value 0.001 r 0.37 and R square 0.138), LDL (p value 0.002 r 0.35 and R square 0.128), HDL (p value 0.001, r 0.37 and R square 0.139) and TG (p value 0,002, r 0.36 and R square 0.130). The result of study was found that lead exposure contributed on blood pressure and lipid parameters alteration among people around bus terminal in Yogyakarta.
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