Refine your search
Collections
Co-Authors
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Chakraborty, Indrani
- Jussiaea repens as a Herbal Cotraceptive-A Mating Study in Male Rats
Abstract Views :1250 |
PDF Views:3
Authors
Subhasis Ghoshal
1,
Arnab Das
2,
Kajari Bhattacharya
2,
Maitrayee Mondal
2,
Indrani Chakraborty
3,
Nimai Masanta
4,
Nirmal Pradhan
2
Affiliations
1 Dept. of Physiology, Presidency University, Kolkata, West Bengal, IN
2 P. G. Dept. of Physiology, Hooghly Mohsin College, Chinsurah, Hooghly, West Bengal, IN
3 Dept. of Physiology, Krishnanagar Govt. College, Nadia, West Bengal, IN
4 Dept. of Physiology, Jhargram Raj College, Paschim Medinipur, West Bengal, IN
1 Dept. of Physiology, Presidency University, Kolkata, West Bengal, IN
2 P. G. Dept. of Physiology, Hooghly Mohsin College, Chinsurah, Hooghly, West Bengal, IN
3 Dept. of Physiology, Krishnanagar Govt. College, Nadia, West Bengal, IN
4 Dept. of Physiology, Jhargram Raj College, Paschim Medinipur, West Bengal, IN
Source
Journal of Environment and Sociobiology, Vol 12, No Sp Iss (2015), Pagination: 20-20Abstract
Jussiaea repens (locally called Kesardam) is a medicinal herb in different countries in the world. It grows in wetlands and is also used as vegetables and animal-forage. In Papua New Guinea leaves and stems of this plant are considered as contraceptive in preventing pregnancy. But suitable studies of this plant on male reproduction are yet not available. The present study was designed to investigate the anti-gonadal property of J. repens in male rats through mating studies. The aqueous extract of J. Repens at oral dose of 200 mg/kg b.wt/day for 28 days caused no signifcant change in b.wt but weight of testis and cauda epididymis, sperm motility, total sperm count from cauda epididymis, sperm viability and normal sperms were signifcantly reduced implantation site where in control it was 100% fertility and 10.7 implantation sites. In recovery group, 87.5% fertility and 9.8 implantation sites were observed per rat. This is near to normal. Withdrawal of drug for successive 28 days caused marked recovery in testicular and epididymal weight, sperm motility, count, viability and morphology possibly due to inhibition of spermatogenesis and steroidogenesis. The reversal studies caused recovery of reproductive parameters towards normal revealing the nontoxicity. So the present study may confrm the anti-fertility effect of J. repens. Therefore, it may be used as herbal male contraceptive.
- Jussiaea repens as a Herbal Cotraceptive - A Mating Study in Male Rats
Abstract Views :480 |
PDF Views:1
Authors
Subhasis Ghoshal
1,
Arnab Das
2,
Kajari Bhattacharya
2,
Maitrayee Mondal
2,
Indrani Chakraborty
3,
Nimai Masanta
4,
Nirmal Pradhan
2
Affiliations
1 Department of Physiology, Presidency University, Kolkata, West Bengal, IN
2 Post Graduate Dept. of Physiology, Hooghly Mohsin College, Chinsurah, Hooghly, West Bengal, IN
3 Department of Physiology, Krishnanagar Govt. College, Nadia, West Bengal, IN
4 Department of Physiology, Jhargram Raj College, Paschim Medinipur, West Bengal, IN
1 Department of Physiology, Presidency University, Kolkata, West Bengal, IN
2 Post Graduate Dept. of Physiology, Hooghly Mohsin College, Chinsurah, Hooghly, West Bengal, IN
3 Department of Physiology, Krishnanagar Govt. College, Nadia, West Bengal, IN
4 Department of Physiology, Jhargram Raj College, Paschim Medinipur, West Bengal, IN
Source
Journal of Environment and Sociobiology, Vol 12, No 1 (2015), Pagination: 123-131Abstract
Wetland plant, Jussiaea repens (locally called Keshardam) is a medicinal herb in different countries in the world. It is also used as vegetables and animal-forage. In Papua New Guinea, the leaves and stems of the plant are considered as contraceptive in preventing pregnancy. But no suitable studies on antifertility effect of J. repens in males are yet available. The present study was designed to investigate the anti-gonadal property of J. repens in male rats through mating studies. The aqueous extract of J. repens at oral dose of 200 mg/kg b.wt/day for 28 days caused no significant change in body weight but weight of testis and cauda epididymis, sperm motility, total sperm count from cauda epididymis, sperm viability and normal sperms were signifi cantly reduced in treated group. The mating studies with treated group showed 25% fertility having '0' implantation site whereas in control it was 100% fertility and 10.7 implantation sites. In recovery group, 87.5% fertility and 9.8 implantation sites were observed per rat, which is near to normal. Withdrawal of drug for successive 28 days caused marked recovery in testicular and epididymal weight, sperm motility, count, viability and morphology possibly due to inhibition of spermatogenesis and steroidogenesis. The reversal studies caused recovery of reproductive parameters towards normal revealing the nontoxicity. So the present study may confi rm the anti-fertility effect of J. repens. Therefore, it may be used as herbal male contraceptive.Keywords
Jussiaea repens, Medicinal Herb, Antigonadal, Herbal Male Contraceptive, Male Reproduction.References
- Bjorndahl, L., Soderlund, l. and Kvist, U. 2003. Evaluation of the one-step eosin nigrosin staining technique for human sperm vitality assessment. Hum Repord., 18: 813-816.
- Chitra, K. C., Latchaumycanda, E. and Mathur, P. P. 2001. Chronic effect of endosulfan on the testicular functions of rats. Asian J. Androl., 1: 203-206.
- Chinoy, N. J., D'Souza, T. M. and Padman, P. 1995. Contraceptive efficacy of Carica papya seed extract in male mice (Mus musculus). Phytother. Res., 9: 30-36.
- Hawk, P. B. and Oser, B. L. 1976. In: Hawk's Physiological Chemistry, (Ed. B.L.Oser), 14th ed. Tata McGraw Hill, New Delhi, pp. 1376.
- Lampiao, F. 2013. The antifertility effects of Acacia nilotica in male wistar rats. J. Reperod Infertil., 14(54), Issue 1: 39-42.
- Marzouk, M. S., Soliman, F. M., Shehata, I. A., Rabee, M. and Fawzy, G. A. 2007. Flavonoids and biological activites of Jussiaea repens. Nat. Prod. Res., 21(5): 436-443.
- Oben, J. E. Assise., Agbor, G .A. and Musoro, D. F. 2006. Effect of Eremomastax speciosa on experimental diarrhea. Afr. J. Tradit. Complement Altern. Med., 3(1): 95-100.
- Ochigu, Shedark, Uchendu, I., Anwocha, C., Ihedi, Oha and Ikechukwu, J. A. 2006. New and simple method of confi rmatory detection of mating in albino rats (Rattus norvegicus). Animal Reaserch International, 3(3): 572-530.
- Orlu, E. E. and Ogbalu, O. K. 2012. Little size, sex ratio and some liver biomarkers in sprague-dawley rats recovering from exposure to ethanol extract of Lepideagathis alopecuroides. Current Research Journal of Biological Sciences, 4(5): 643-648.
- Parekh, J. and Chanda, S. 2007. Invitro antimicrobial activity of T. rapanatans L. fruit rind extracted in different solvents. Afr. J. Biotechnol., 6(16): 1905-1909.
- Pradhan, N., Ghoshal, S. and Chakroborty, I. 2013. Jussiaea repens L is a non toxic antigonadal herb a dose dependent study on male rats. Int. J. pharm. Biol. Sci., 4(2): 131-143.
- Serrentino, J. 1991. How Natural Remedies Work. (ed. Point Robert, W. A.) Harley and Marks Publishers, pp. 20-22.
- Singh, A., Kala, S. and Kapoor, D. N. 2011. Reversible contraceptive effi cacy and sefty evaluation of ethanolic extract of Tinospora cordifolia in animal model. Archives of Applied Science Research, 3(5):587-592.
- Thanabhorn, S., Jaijoy, K., Thamaree, S., Ingkaninan, K. and Panthong. A. 2006. Acute and subacute toxicity study of the ethanol extract from Lonicera japonica Thumb. Ethanopharmacol., 107: 370-373.
- Wainright, M. 2001. The story of penicillin and the golden age of antibiotics. Miracle cure, pp. 237.
- World Health Organization, 1999. WHO Laboratory Manual for the examination of human semen and sperm-cervical Mucus Interactions, 4th ed., Cambridge University Press, Cambridge, United Kingdom.
- Wyrobek, A. J., Marchetti, F., Sloter, E. and Bishop, J. 2001.Chromosomally defective sperm and their developmental consequences, In: Anderson, D. (ed.). Human monitoring after environmental and occupational exposure to chemical and physical agents. NATO ASI Series.
- Yama, O. E., Osinubi, A. A., Duru, F. I. O., Noronha, C. C. and Okanlawon, A. O. 2011. Contraceptive effect of methanolic extract of Momordica charantia seed in male sprague-dawley rats. Asian Journal of Pharmaceutical and Clinical Research, 4(2): 22-26.
- Zemjanis, R. 1997. Collection and evaluation of semen, In: Diaginostic and Therapeutic Techniques in Animal Reproduction. William and Wilkins company, Baltimore, USA. pp. 242.
- Studies of Antidiabetic Property in Jussiaea repens in Alloxan Induced Male Rats
Abstract Views :280 |
PDF Views:1
Authors
Tasneem Khandelkar
1,
Ayan Roy
1,
Soumitri Bhoumik
1,
Nirmal Kr. Pradhan
1,
Maitreye Mukherjee
1,
Dipan Adhikary
2,
Indrani Chakraborty
3,
Subhasish Ghosal
4
Affiliations
1 PG Dept. of Physiology, Hooghly Mohsin College, Hooghly, IN
2 PG Dept. of Botany, Hooghly Mohsin College, Hooghly, IN
3 Dept. of Physiology, Krishnanagar Govt. College, Nadia, IN
4 Dept. of Physiology, Presidency University, Kolkata, IN
1 PG Dept. of Physiology, Hooghly Mohsin College, Hooghly, IN
2 PG Dept. of Botany, Hooghly Mohsin College, Hooghly, IN
3 Dept. of Physiology, Krishnanagar Govt. College, Nadia, IN
4 Dept. of Physiology, Presidency University, Kolkata, IN