Journal of Endocrinology and Reproduction

M. Sridhar ¹, P. Venkataraman ¹, S. Dhanammal ¹, A. Arunkumar ¹, K. Balasubramanian ¹, M. M. Aruldhas ¹, J. Arunakaran ¹

Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, IN

Abstract

The present study was conducted to determine the effect of Aroclor 1254 (2 mg/kg bwt/day/IP) for 30 days, induced oxidative stress in prostate of adult albino rats. Additionally antioxidants such as Quercetin (2 mg/kg bwt/day/oral), Vitamin C (500 mg/kg bwt/day/oral) and Vitamin E (50 mg/kg bwt/ day/oral) were administrated to evaluate their therapeutic potency against Aroclor 1254 induced stress for 10 days.

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S. Dhanammal ¹, M. Sridhar ¹, P. Venkataraman ¹, M. R. Vijayababu ¹, K. Balasubramanian ¹, M. M. Arlildhas ¹, J. Arunakaran ¹

Affiliations
1 Department of Endocrinology, Dr. ALMPGIBMS, University of Madras, Taramani, Chennai-600 113, IN

Abstract

The present study was aimed to evaluate the effect of Aroclor 1254 (2mg/kg bwt/day/ip/30 days) induced oxidative stress in epididymis of adult albino rats. Antioxidants such as vitamin C (500mg/kg bwt/day/oral) were administered for 10 days to counter the effect of Aroclor 1254 induced oxidativestress.

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P. Venkataraman ¹, M. Sridhar ¹, S. Dhanammal ¹, P. Murugesan ¹, J. Arunakaran ¹, N. Srinivasan ¹, M. M. Aruldhas ¹

Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600113, IN

Abstract

Effects of quercetin, vitamin C and E on PCB exposed ventral prostaitc zinc content were studied in adult albino rats, a group of 20 rats were treated with Aroclor 1254 (2 mg/kg bwt/day/IP) for 30 days. Five rats were treated as PCB control. The remaining 15 rats were subdivided into the following subgroups of five animals each. They were given vitamin C (500 mg/kgbwt/day/oral) for 10 days; vitamin E (50 mg/kg bwt/day/oral) for 10 days; quercetin (2 mg/kg bwt/day/oral) for 10 days.

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