Journal of Endocrinology and Reproduction

R. Chaube ¹, K. P. Joy ¹

Affiliations
1 Department of Zoology, Banaras Hindu University, Varanasi 221 005, IN

Abstract

In the present in vitro study, involvement of cAMP in basal and E₂-modulated brain (hypothalamus and telencephalon) TH activity was demonstrated in female catfish Heteropneustes fossilis. Incubation of enzyme preparation (soluble active fraction) with cAMP (0.05-1 .OmM) and inhibitors of cAMP-specific phosphodiesterase (IBMX, 0.5-2.0mM) and theophylline, 0.5-2.0mM) stimulated enzyme activity in a concentration-dependent manner.

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