Journal of Endocrinology and Reproduction

E. Prabakaran ¹, P. Prabakaran ², N. Subramanian ¹

Affiliations
1 Department of Zoology, Presidency College, Chennai 600 005, IN
2 Department of Zoology, Chellammal Women's College, Chennai, IN

Abstract

About 43 women patients affected by carcinoma of cervix were categorized into three groups namely Grade I (well differentiated squamous cell carcinoma). Grade II (Moderately differentiated). Serum lactate dehydrogenase isoenzymes of these groups of women affected by carcinoma of cervix were analyzed by PAGE and were compared with those of normal individual.

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R. Krishnamurthy ¹, E. Prabakaran ¹, P. Prabakaran ²

Affiliations
1 Department of Zoology, Presidency College, Chennai-600 005, IN
2 Chellammal Women's College, Chennai-600 032, IN

Abstract

Lactate dehydrogenase of testis were analyzed in normal healthy male mice. There were five LDH fraction corresponding to LDH1, LDH2, LDH3, LDH4 and LDH5. The activity of these five fracfions were 28%, 32%, 14%, 11% and 15%, respectively. In alloxan induced diabetics mice, there was remarkable change in the testis LDH pattern as well as well as its activity. There was significant increase in the number of fractions to eight. Two new fractions appeared between LDH1 and LDH2 and one fraction appeared between LDH4 and LDH5. The activity of LDH1 increased to 35%, LDH3 to 25% while those of all other fractions decreased.

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