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Balaganesh, M.
- Regulation of Rat Bone Marrow Stem Cells Differentiation into Osteoblasts and Mineralization by Estrogen
Abstract Views :169 |
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Authors
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, IN
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 43-43Abstract
The age-related defects in osteoblast number and function may be due to quantitative and qualitative stem cell defects. Early commitment and conversion of bone marrow stem cells (BMSCs) towards osteoblastic lineage is a critical step in the process of bone formation and bone remodeling, which is regulated by various systemic hormones and local factors. There are a few studies that analyze whether changes in the functional characteristics of osteoblastic progenitor cells, the BMSCs.
- Role of RhTGF-β1 on Differentiation and Mineralization of Rat Bone Marrow Stem Cells
Abstract Views :180 |
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Authors
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600113, IN
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600113, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 72-72Abstract
Bone marrow is a complex tissue, which contains stem cells for haematopoietic and mesenchymal lineage. Among various growth factors that regulate bone remodeling, TGF-bl is the major growth fator, which is synthesized and stored in bone in large amount. But, the exact role of TGF-bl on the differentiation and mineralization of bone marrow stem cells (BMSCs) is still not clear. Hence, the present study is designed to delineate the role of rhTGF-bl on the differentiation and mineralization of rat BMSC in vitro. Bone marrow stem cells were isolated from the femur bones of healthy rats and cultured with osteogenic medium (OM).- Effect of 17β-Estradiol on IGFBP-3 Production and Differentiation of SAOS-2 Cells in Vitro
Abstract Views :196 |
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Authors
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600 113, IN
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600 113, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 81-81Abstract
Bone formation is a dynamic process, which is regulated by various hormones and local growth factors. Numerous clinical and experimental studies have shown that estrogen deficiency delays the maturation of the skeleton and interferes with the normal growth of the bones.- Serum Dihydrotestosterone is a Major Determinant of Bone Mineral Density in Men
Abstract Views :234 |
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Authors
R. llangovan
1,
M. Balaganesh
1,
S. Sittadjody
1,
R. Sivakumar
1,
M. Sridhar
1,
R. C. Vignesh
1,
B. Ravi Sankar
1,
J. Arunakaran
1,
K. Balasubramanian
1,
M. Michael Aruldhas
1,
N. Srinivasan
1
Affiliations
1 Department of Endocrinology, Dr. ALM PG Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai - 600 113, IN
1 Department of Endocrinology, Dr. ALM PG Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai - 600 113, IN