Journal of Endocrinology and Reproduction

R. Ilangovan ¹, S. Sitta-Djody ¹, H. M. Balaganes ¹, N. A. Jayavelan ², M. S. Holi ², N. Srinivasan ¹

Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medicai Sciences, Chennai 600113, IN
2 Institute Hospital, Biomedical Engineering Division, IIT Madras, Chennai 600 036, IN

Abstract

Osteoporosis is characterized by impairment of bone mass and deterioration of bone microscopic structure, resulting in increased bone fragility and susceptibility to fracture. Osteoporosis is considered as a postmenopausal woman's disease; however, recent studies indicate that the effects of this disease in men are at least as severe as in women. Insulin-like growth factors (IGFs) and its binding proteins (IGFBPs) are known to influence the bone physiology.

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