Journal of Endocrinology and Reproduction

G. B. N. Chainy ¹, S. Luna ¹

Affiliations
1 Department of Biotechnology, Utkal University, Bhubaneswar-751004, IN

Abstract

Over the past several decades, diabetes mellitus, has become a major health problem worldwide, reaching epidemic proportions in many developing countries. The global prevalence of diabetes is estimated to increase fi-om 4% in 1995 to 5.4% by the year 2025. The countries with the largest number of diabetics are, and will be in the year 2025, India, China and United States.

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S. Chattopadhyay ¹, K. Das ¹, G. B. N. Chainy ¹

Affiliations
1 Department of Zoology & Biotechnology, Utkal University, Bhubaneswar-751004, IN

Abstract

The heart tissue is considered highly responsive to thyroid hormones. However, the functional aspect of cardiac mitochondria in this context is not yet fiilly elucidated. The present work for the first time attempts to highlight the possible effects of thyroid hormone on peroxidative stress in mitochondrial milieu of rat heart with respect to its primary antioxidant capacity. The antioxidant enzymes of post-mitochondrial fraction (PMF) were also investigated for comparative purpose.

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