Journal of Endocrinology and Reproduction

M. B. Hiremath ¹, B. B. Kaliwal ¹

Affiliations
1 Reproductive Toxicology Laboratory, Post-graduate Department of Studies in Biotechnology and Microbiology, Karnataka University, Dharwad 580 003, IN

Abstract

Endosulfan, a chlorinated pesticide was administered orally to virgin mice at an effective dose of 4 mg/kg body weight/day for days 5, 10, 20 and 30 to examine its durational effect on estrous cycle, follicular kinetics and biochemical constituents in mice.

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M. P. Mahadevaswami ¹, B. B. Kaliwal ¹

Affiliations
1 Reproductive Toxicology Laboratory, Post-graduate Department of Studies in Biotechnology and Microbiology, Kamataka University, Darwad-5 80003, IN

Abstract

Dimethoate, an organopho-sphorus pesticide was administered orally to virgin pregnant mice at doses of 16,20,24 and 28mg/kg body weight/day for 7 consecutive days to examine its effect on blastocyst implantation. Control mice received similar quantities of distilled water. Autopsy on day 8 revealed that the distilled water treated mice were pregnant and had a normal number of implantations and normal duration of diestrus. Treatment with 16 and 20mg/kg/day diethoate neither inhibited implantation nor significantly changed diestrus.

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U. C. Jadarmukunti ¹, B. B. Kaliwal ²

Affiliations
1 Reproductive Toxicology Laboratory, Post-Graduate Department of Studies in Biotechnology and Microbiology, Kamatak University, Dharwad-580003, IN
2 Reproductive Toxicology Laboratory, Post-Graduate Department of Studies in Biotechnology and Microbiology, Kamatak University, Dharwad-5 80003, IN

Abstract

The present study was undertaken with an objective of assessing the antigonadal effect of exogenous melatonin injections in ovarian follicular growth during compensatory ovarian hypertrophy. Female rats exhibiting regular estrous cycle were unilaterally ovariectomised and melatonin was administered at the dose rates of 10,20 and 40 micrograms to these rats divided in groups (n=3D6). The control was injected with normal saline. All the administrations were made at 16:00 hours and started from day zero of unilateral ovariectomy and continued for 3 consecutive days.

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