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Application of Design of Experimental Technique for Optimization of Product Characteristics in the Solution Combustion Processing of Phase Pure Nano-HAp


Affiliations
1 Department of Biomedical Engineering, Netaji Subhas engineering College, Kolkata, India
2 Department of Instrumentation Science, Jadavpur University, Kolkata, India
3 Department of Mechanical Engineering, Asansol Engineering College, Asansol, India
     

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Calcium hydroxy apatite, Ca10(PO4)6(OH)2 (HAp) nano-sized biomaterial was processed chemically by solution combustion method using calcium nitrate-di-ammonium hydrogen orthophosphate and glycine as fuels. Calcium Hydroxyapatite is an important bio-material for orthopedic applications. A series of solution combustion reactions were used to optimize the process parameters for synthesis of very fine HAp bio-ceramic powders. The combustion flame temperature (Tf) at stoichiometric fuel to oxidant ofthe solution combustion process was calculated to be 883° C. In the present work, correlations of various process parameters and the flame temperature as well as the specific surface area (SSA) of as synthesized powder were established. Both Taguchi and a regression model were used in this process to correlate the input parameters and output parameter of this system. The adequacy ofthe mathematical model was justified by using the analysis of variance technique. In this present investigation, nano-sized particles in the range of 20-130 nm was successfully processed through optimized process parameters.

Keywords

DOE, Optimization, Product Characterisitics, Solution Contribution Nano-Material, Biomaterial, HAp.
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  • Application of Design of Experimental Technique for Optimization of Product Characteristics in the Solution Combustion Processing of Phase Pure Nano-HAp

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Authors

Anupam Maiti
Department of Biomedical Engineering, Netaji Subhas engineering College, Kolkata, India
Samir Kumar Ghosh
Department of Biomedical Engineering, Netaji Subhas engineering College, Kolkata, India
Sankar Narayan Patra
Department of Instrumentation Science, Jadavpur University, Kolkata, India
Debashis Sarkar
Department of Mechanical Engineering, Asansol Engineering College, Asansol, India

Abstract


Calcium hydroxy apatite, Ca10(PO4)6(OH)2 (HAp) nano-sized biomaterial was processed chemically by solution combustion method using calcium nitrate-di-ammonium hydrogen orthophosphate and glycine as fuels. Calcium Hydroxyapatite is an important bio-material for orthopedic applications. A series of solution combustion reactions were used to optimize the process parameters for synthesis of very fine HAp bio-ceramic powders. The combustion flame temperature (Tf) at stoichiometric fuel to oxidant ofthe solution combustion process was calculated to be 883° C. In the present work, correlations of various process parameters and the flame temperature as well as the specific surface area (SSA) of as synthesized powder were established. Both Taguchi and a regression model were used in this process to correlate the input parameters and output parameter of this system. The adequacy ofthe mathematical model was justified by using the analysis of variance technique. In this present investigation, nano-sized particles in the range of 20-130 nm was successfully processed through optimized process parameters.

Keywords


DOE, Optimization, Product Characterisitics, Solution Contribution Nano-Material, Biomaterial, HAp.

References





DOI: https://doi.org/10.22485/jaei%2F2019%2Fv89%2Fi1-2%2F185673