Informatics Publishing Limited

Deepak Prashar ¹, Sanjay Kumar ², Surender Sharma ³, Pankaj Thakur ³, Luder Mani ³

Affiliations
1 Department of Pharmaceutical Sciences, Vinayaka College of Pharmacy, Kullu (H.P.), IN
2 Department of Economics, Govt. College, Dharampur, Mandi (H.P.), IN
3 Department of Pharmaceutical Sciences, Vinayaka College of Pharmacy, Kullu (H.P.),, IN

Abstract

Liposomes are one among the best drug carrier available in the present scenario. The pharmaceutical field is utilizing this drug carrier in the best way. Its site specific drug delivery property makes it the deserving candidate for targeted drug delivery system. The economical aspect of any product provides an opportunity to decide its utility. The present review tries to explore the economical overview as well as the international market scenario of the liposomes.

Keywords

Liposomes, Drug Carrier, Economical, World Market

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Poonam Sharma ¹, Shweta Sachar ², Gurpreet Kaur ³, Pankaj Thakur ¹, Mandeep Singh Bakshi ³, Tarlok Singh Banipal ¹

Affiliations
1 Department of Applied Chemistry, Guru Nanak Dev University, Amritsar 143 005, (Punjab), IN
2 Department of Chemistry and Centre of Advanced Studies, Panjab University, Chandigarh, 160 014, IN
3 Department of Chemistry, Guru Nanak Dev University, Amritsar 143 005, (Punjab), IN

Abstract

The mixed micellar properties of a sugar surfactant dodecyl-β-D-glucopyranoside (β-C12G) with a series of cationic gemini surfactants in aqueous solution have been investigated at different temperatures, i.e., 288, 298, 308, and 318 K. The steady state fluorescence measurements have been carried out to calculate critical micelle concentrations (cmc) for the various binary combinations of β-C12G+12-0-12/12-2-12/12-6-12. The composition of the mixed micelles and the interaction parameter (β) were evaluated from the cmc data for these mixtures. The binding constant (K_sv) of the mixed systems were determined from the ratio of intensity of peaks (I_o/I) of the pyrene fluorescence emission spectrum. It has been concluded that there is a difference in mixed micellar behavior of b-C12G with 12-0-12, 12-2-12, and 12-6-12. This difference is due to the dimeric nature and increase in the number of methylene groups of the spacer.

Keywords

Sugar Amphiphiles, Synergism, Mixed Micelles, Fluorescence Measurements.

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