International Journal of Nursing Education and Research

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Psychiatric Clients with Toxocara-A Critical Review and Research Gap Analysis


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1 Mental Health Nursing Department, Dhanvantri College of Nursing, Pallakkapalayam, Namakkal, Tamilnadu, India
     

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Toxocariasis is asymptomatic as the larvae are unable to reproduce and subsequently die, but local inflammation can lead to distinct syndromes depending on where in the body the larvae reside. In rare cases these larvae may migrate to the central nervous system where they may cause a constellation of neurological symptoms including meningoencephalitis, focal deficits and seizures. The reports of toxocariasis shows causative factor of psychiatric symptoms. Several studies have highlighted the increased seroprevalence of antitoxocara antibodies in psychiatric populations particularly schizophrenia, although it is uncertain whether is a causative effect or secondary to the population’s increased likelihood to behave strangely or be homeless. Recently, there has been interest in the possible association between neurotoxocariasis and an immune-mediated dementia.
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  • Ahn SJ, Woo SJ, Jin Y, Chang YS, Kim TW, Ahn J, Heo JW, Yu HG, Chung H, Park KH, Hong ST 2014. Clinical features and course of ocular toxocariasis in adults. PLoS Negl Trop Dis; 8:e2938.

  • Cosme Alvarado-Esquivel, Jesus Hernandez-Tinoco, Luis Francisco Sanchez-Anguiano, and Jorge Arturo Cisneros-Martinez, 2014. Low Seroprevalence of Toxocara Infection in Schizophrenic Inpatients in Durango, Mexico: A Case Control Study. Int J Biomed Sci. Dec; 10(4): 269-271.

  • Dar ZA, Tanveer S, Yattoo GN, Sofi BA, Wani SA, Dar PA, Fomda BA, 2008. Seroprevalence of toxocariasis in children in Kashmir, J and K State, India. Iran J Parasitol; 3(4):45-50.

  • De Savigny DH, Voller A, Woodruff AW, 1979.Toxocariasis: serological diagnosis by enzyme immunoassay. J Clin Pathol; 32:284-288.

  • Ehrard T, Kernbaum S, 1979. Toxocara canis et toxocarose humaine. Bull Inst Pasteur; 77:225-287.

  • El-Sayed NM, Ismail KA, 2012. Relationship between Toxocara canis infection and schizophrenia. Rawal Medical Journal; 37(2):155-60.

  • Fellrath JM, Magnaval JF, 2014. Toxocariasis after slug ingestion characterized by severe neurologic, ocular, and pulmonary involvement. Open Forum Infect Dis; 1(2):ofu063.

  • Fisher M, 2003. Toxocara cati: an underestimated zoonotic agent. Trends Parasitol; 19:167-170.

  • Glickman LT, Magnaval JF, Domanski LM, Shofer FS, Lauria SS, Gottstein B, Brochier B 1987. Visceral larva migrans in French adults. A new disease syndrome? Am J Epidemiol; 125:1019-1033.

  • Holland CV, Hamilton CM, 2013. The significance of cerebral toxocariasis: a model system for exploring the link between brain involvement, behaviour and the immune response. J Exp Biol; 216:78-83

  • Huminer D, Symon K, Groskopf I, Pietrushka D, Kremer I, Schantz PM et al, 1992. Seroepidemiologic study of toxocariasis and strongyloidiasis in institutionalized mentally retarded adults. Am J Trop Med Hyg; 46:278-81.

  • Kaplan M, Kalkan A, Kuk S, et al, 2008. Toxocara Seroprevalence in Schizophrenic Patients in Turkey. Yonsei Med J; 49(2):224-9.

  • Khante GS, Khan LA, Bodkhe AM, Suryawanshi PR, Majed MA, Suradkar US, Gaikwad SS, 2009. Epidemiological survey of gastrointestinal parasites of non-descript dogs in Nagpur city. Vet World; 2(1): 22-23.

  • Lawton S, Sharma A, 2017. Psychiatric manifestations of Toxocara Progress in Neurology and Psychiatry Vol. 21 Iss. 1: 22-23.

  • M. Assmar, A. Amirkhani, N. Piazak, A. Hovanesian, A. Kooloobandi, and R. Etessami, 1997, “Toxoplasmosis in Iran, results of a seroepidemiological investigation,” Bulletin de la Societe de Pathologie Exotique, vol. 90, no. 1, pp. 19-21.

  • Macpherson CN, 2013. The epidemiology and public health importance of toxocariasis: a zoonosis of global importance. Int J Parasitol; 43(12–13): 999-1008.

  • Magnaval JF, Charlet JP 1987. Efficacité comparée du thiabendazole et du mébendazole dans le traitement de la toxocarose. Therapie; 42:541-544. [PubMed].

  • Mustafa Kaplan, Ahmet Kalkan, Salih Hosoglu, Salih Kuk, Mehmet Ozden, Kutbedtin Demirdag, Aykut Ozdarendeli, 2004. The frequency of Toxocara infection in mental retarded children. Mem. Inst. Oswaldo Cruz vol.99 no.2 Rio de Janeiro.

  • Nagwa Mostafa El-Sayed, Khadiga Ahmed Ismail, 2012. Relationship between Toxocara canis infection and schizophrenia. Rawal Medical Journal 37(2):155-160.

  • Richartz E, Buchkremer G, 2002. Cerebral toxocariasis: a rare cause of cognitive disorders. A contribution to differential dementia diagnosis. Nervenarzt; 73(5):458–62. Turkey. Yonsei Med J; 49(2): 224-9.

  • Shahram Khademvatan, Niloufar Khajeddin, Sakineh Izadi and Elham Yousefi, 2014. Investigation of Anti-Toxocara and Anti-Toxoplasma Antibodies in Patients with Schizophrenia Disorder. Schizophrenia Research and Treatment. Hindawi Publishing Corporation: 1-7.

  • Subhash K, Tanwar RK, 2007. Prevalence of worm infestation in stray dogs in and around Jodhpur. J vet Parasitol; 21(2):171-172.

  • Traub RJ, Robertson ID, Irwin P, Mencke N, Thompson ARC, 2002. The role of dogs in transmission of gastrointestinal parasites in a remote tea-growing community in northeastern India. Am J Trop Med Hyg; 67(5):539-545.


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  • Psychiatric Clients with Toxocara-A Critical Review and Research Gap Analysis

Abstract Views: 198  |  PDF Views: 0

Authors

W. Sampoornam
Mental Health Nursing Department, Dhanvantri College of Nursing, Pallakkapalayam, Namakkal, Tamilnadu, India

Abstract


Toxocariasis is asymptomatic as the larvae are unable to reproduce and subsequently die, but local inflammation can lead to distinct syndromes depending on where in the body the larvae reside. In rare cases these larvae may migrate to the central nervous system where they may cause a constellation of neurological symptoms including meningoencephalitis, focal deficits and seizures. The reports of toxocariasis shows causative factor of psychiatric symptoms. Several studies have highlighted the increased seroprevalence of antitoxocara antibodies in psychiatric populations particularly schizophrenia, although it is uncertain whether is a causative effect or secondary to the population’s increased likelihood to behave strangely or be homeless. Recently, there has been interest in the possible association between neurotoxocariasis and an immune-mediated dementia.

References