The Indian Journal of Nutrition and Dietetics

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Phytochemical Screening and Anti-Diabetic Efficacy of O. sanctum Seed Extract on Streptozotocin Induced Diabetic Rats


Affiliations
1 Department of Foods and Nutrition, Vellalar College for Women, Erode, Tamilnadu, India
     

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The present study was designed to assess the in vitro and in vivo anti-diabetic efficacy of O. sanctum seed and its phytochemical screening. In vitro inhibitory effect on carbohydrate digestive enzymes like α-amylase and α-glucosidase and in vivo parameters such as fasting blood glucose and body weight changes were studied, a potent inhibitory effect was observed on activities of digestive enzymes and a marked decrease in the glucose level in the O. sanctum seed extract treated streptozotocin induced diabetic rats was noted. Further a marked reduction in body weight was also observed.

Keywords

Ocimum sanctum Seed, Anti-Diabetic Activity, Phytochemicals.
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  • Phytochemical Screening and Anti-Diabetic Efficacy of O. sanctum Seed Extract on Streptozotocin Induced Diabetic Rats

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Authors

K. Kavitha
Department of Foods and Nutrition, Vellalar College for Women, Erode, Tamilnadu, India
S. Ponne
Department of Foods and Nutrition, Vellalar College for Women, Erode, Tamilnadu, India

Abstract


The present study was designed to assess the in vitro and in vivo anti-diabetic efficacy of O. sanctum seed and its phytochemical screening. In vitro inhibitory effect on carbohydrate digestive enzymes like α-amylase and α-glucosidase and in vivo parameters such as fasting blood glucose and body weight changes were studied, a potent inhibitory effect was observed on activities of digestive enzymes and a marked decrease in the glucose level in the O. sanctum seed extract treated streptozotocin induced diabetic rats was noted. Further a marked reduction in body weight was also observed.

Keywords


Ocimum sanctum Seed, Anti-Diabetic Activity, Phytochemicals.

References