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Mehta, Dilip
- Relevance of Fast Track Integrative Approaches for the Control of COVID-19
Authors
1 Managing Director, Pharmanza Herbal Pvt. Ltd. Gujarat, IN
2 CEO, Synergia Life Sciences Pvt. Ltd. Mumbai, IN
3 Director, Division of Endocrine and Metabolic Disorders, Medical and Research Centre - Kasturba Health Society, Mumbai, IN
4 Research Director, Kasturba Health Society-Medical Research Centre, Mumbai, IN
Source
The Indian Practitioner, Vol 73, No 5 (2020), Pagination: 44-47Abstract
The current global pandemic of COVID-19 has spread over 212 countries with marked morbidity and substantial mortality. This has resulted in colossal burden on the worldwide healthcare system. Globally the management of this new disease is primarily supportive and resuscitative. Vaccine and anti-COVID-19 drugs are still under development. Oriental medicine of India and China and the medicinal plants offer a potential for a fast track development of phytopharmaceuticals. In the present overview we have shortlisted the following Indian medicinal plants, based on their traditional usage and scientific rationale: Phyllanthus amarus Schum and Thonn., Berberis aristata DC., Swertia chirata and Androgaphis paniculata (Burm. f.). These medicinal plants and the phytoactives can be rapidly evaluated for anti-COVID-19 activity through reverse pharmacology.Keywords
COVID-19, Reverse Pharmacology, Medicinal Plants, Antiviral Activity, Phytopharmaceuticals.References
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- Vitamin K2 Insufficiency: Linking Acute Respiratory Distress Syndrome and Coagulopathy in Severity of COVID-19
Authors
1 Assistant Medical Director, Viridis BioPharma Pvt. Ltd., Mumbai, Maharashtra- 400071, IN
2 CEO, Synergia Life Sciences Pvt. Ltd. Mumbai, Maharashtra- 400071, IN
Source
The Indian Practitioner, Vol 75, No 2 (2022), Pagination: 26-33Abstract
The recent pandemic due to Coronavirus Disease-19 (COVID-19) has been a very dreadful situation for mankind. It took a toll on every sector in the world besides the common people. Understanding the disease and its management on a fast-track was a big challenge to clinicians and researchers. The root cause of death due to COVID-19 was pneumonia and acute respiratory distress syndrome (ARDS). Several pathophysiological mechanisms involving lung damage, vascular coagulopathy and inflammation have been identified. Besides key risk factors viz. advanced age and comorbidities, insufficiency of micronutrients and vitamins is known to increase severity of the disease. Vitamin C and D supplementation was one of the components of the treatment algorithm in the management of COVID-19. Another vitamin, Vitamin K has been linked to COVID-19-associated severity. The present article reviews the scientific basis of this emerging notion and gives an overview of the types of Vitamin K– K1 and K2 with emphasis on Vitamin K2-7 and its functional benefits in reducing COVID 19-related morbidity and mortality.
Keywords
COVID-19, coronavirus, nutrient insufficiency, vitamin K2-7, ARDS, vascular coagulopathy, cardiovascular complicationsReferences
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