International Journal of Health Research and Medico Legal Practice

Sonowal Basanta ¹, Handique Amitabh ¹

Affiliations
1 Department of Pathology, Tezpur Medical College, Tezpur, Assam, IN

Abstract

Objectives: To evaluate the correlation of AgNOR count and malignant lesions of cervix.

Methods: The material for the study was collected from patient with various lesions of cervix. After colposcopy, a cervical biopsy was done. Routine paraffin sectioning was done for these biopsy specimens. Histopathologic diagnosis was first established on these sections using the routine (H&E) stain. Then, further sections were cut from prepared blocks and were subjected to AgNOR staining technique. AgNOR count was taken as the mean number of black dots per 100 cells observed under a 100× oil immersion objective.

Results: In this series biopsy specimens were obtained and subjected to routine method of haematxoylin and eosin staining which revealed 25% to be benign and 26.6% to be cervical intraepithelial neoplasia and 48.4% cases to be carcinoma.

Conclusion: The results of the AgNOR when used can provide strength to the clinician and histopathologist in diagnosing early carcinoma in cases of suspicious cervix.

Keywords

AgNOR Staining Technique, Malignant Lesion, Cervix.

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Amitabh Handique ¹, Sonowal Basanta ¹

Affiliations
1 Department of Pathology, Tezpur Medical College, Bihaguri, Tezpur, Assam-784010, IN

Abstract

Objective: The aim of this retrospective study is to determine the frequency of ovarian cystic lesions involving both neoplastic and non-neoplastic entities, its distribution and histopathological spectrum including both benign and malignant lesions. Method: This study involved analyzing 67 cases of cystic ovarian lesions/tumors reported in Histopathology section of Tezpur Medical College and hospital in a 24 month period. They were classified according to WHO classification of ovarian tumors (2003). Clinical details of patients were perused according to archived records. Result: Cystic lesions were grouped according to their nature whether neoplastic or non-neoplastic and whether benign, borderline or malignant. The neoplastic cystic lesions comprise the majority of lesions comprising 64.17% while non-neoplastic lesions comprise 35.82%. Among neoplastic lesions cyst adenomas comprise majority (46.5%) of benign lesions and malignant lesions comprise 6.9% of lesions. Among non-neoplastic lesions simple/follicular cysts comprise 54.16% of lesions. Conclusion: Benign cystic neoplastic lesions out number the non-neoplastic lesions and benign tumors are more common than malignant ones. Ovarian lesions are not easily detected by physical or laboratory investigations hence one has to depend in addition to microscopic appearance of the tumor other clinical parameters such as age of the patient, presenting complains, location of lump and dimension of lump.

Keywords

Serous Cyst Adenoma, Papillary Serous Cyst Adenocarcinoma, Undifferentiated Carcinoma.

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