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Saikia, Mayurpankhi
- Pheochromocytoma:A Case Report
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1 Assam Medical College, Dibrugarh, Assam, IN
2 Gauhati Medical College, Guwahati, Assam, IN
1 Assam Medical College, Dibrugarh, Assam, IN
2 Gauhati Medical College, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 3, No 1 (2017), Pagination: 102-104Abstract
Pheochromocytoma refers to the intra adrenal chromaffin neoplasm which is derived from neuroblast from neural crest. Signs and symptoms associated with pheochromocytoma are due to excessive secretion of catecholamines. 65% to 70% cases are sporadic and 30% to35% are manifestation of inherited tumor syndromes. There is germline mutation in gene which encode B, C and D subunit of Succinate dehydrogenase (SDH). Here, we present a case of a 50 year old male patient presenting with paroxysmal attacks of hypertention, palpitation, dizziness, blurring of vision and headache for six month. Clinically he had high systolic and diastolic blood pressure. Radiological imaging studies (CT scan) and abdominal ultrasonography suggested suspected left adrenocortical carcinoma. However histopathological (HP) and immunohistochemical (IHC) examinations confirm the diagnosis of pheochromocytoma. Appropiate diagnosis of pheochromocytoma is important to avoid fatal concequences due to excessive secretion of catecholamines. Moreover, it is a cause of surgically correctable hypertention.Keywords
Pheochromocytoma, Hypertention, Histopathology, Immunohistochemistry.References
- Vinay Kumar, Abul K Abbas, Nelson Fausto. Robbins and Cotran’s Pathologic Basis of Disease. 9thed. Pennsylvania 19106: Elsevier; 2014. p. 1134-35.
- Juan Rosai. Rosai and Ackerman’s Surgical Pathology. 10thed. St Louis, Missouri 63146 : Elsevier; 2004. p. 1076-78.
- Yong L, Sheng-guo D, Zhen D, Xin –yan S. Diagnosis and treatment of Pheochromocytoma in urinary bladder. J Zhejiang Univ Sci B2007;8(6):435-438.
- Christopher DM. Fletcher. Fletcher ’s Diagnostic Histopatholgy of Tumours. 4thed. Philadelphia, PA 191032899: Elsevier; 2013. p. 1308-09.
- Gattuso Paolo, Reddy B. Vijaya, David Odile, Spitz J. Daniel, Haber H, Meryl. Differential Diagnosis in Surgical Pathology. 3rded. Philadelphia. PA 19103-2899: Elsevier; 2015. p. 448-450.
- Lo CY, Lam KY, Wat MS, Lam KS. Adrenal pheochromocytoma remains a frequently overlooked diagnosis. Am J Surg 2000;179:212-215.
- Greene LA, Tischler AS; Tischler. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor”. Proc Natl Acad Sci USA 1976;73(7):2424-8.