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Talukdar, K. L.
- Age Related Histological Changes of Human Spleen
Authors
1 Dept. of Anatomy, Gauhati Medical College, Guwahati, Assam, IN
2 Jorhat Medical College, IN
3 Gauhati Medical College, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 3, No 1 (2017), Pagination: 59-61Abstract
The spleen was a source of intrigue to ancient physician and philosophers. It is the largest lymphoid organ takes important part in body immunity, as high incidences of serious bacterial infections were reported following splenectomy in infancy. A research work was carried out in the department of Anatomy, Gauhati Medical College. The histological characteristics of 21 normal human spleens were studied under light microscope in different age groups and to correlate them functionally. The specimen of spleen varies from newborn to eighty year old cadavers, within stipulated time limit after fulfilling the formalities. The spleens were first washed in normal saline, dried with blotting paper. Tissues were fixed, processed and slides were prepared using standard laboratory procedure of haematoxylin and eosin staining. The size of white pulp that seen on histological sections, increase with age, reach its peak around puberty and then involutes. Sizes of white pulp were measured and then statistically analysed using Student's T-test. P value d" 0.05 is considered as statistically significant. The data obtained in this study will help in certain medico-legal practices and will give insight of different clinical presentations. This study may be used as a podium for further sophisticated studies.Keywords
Human Spleen, White Pulp, Red Pulp, Marginal Zone.Full Text
References
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- Morphological Study of Human Spleen in Different Age Groups
Authors
1 Gauhati Medical Colllege (GMC), IN
2 Jorhat Medical College, Jorhat, IN
3 GMC, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 2, No 2 (2016), Pagination: 77-81Abstract
Spleen is the largest lymphoid organ. It is a haemolymphatic organ containing large amount of lymphatic tissues and plays a vital role in metabolism and defence mechanism of body. It is the largest lymphoid organ and its size varies with individuals' age, sex and underlying metabolic conditions. Spleen takes an important part in body immunity, as high incidences of serious bacterial infections were reported following splenectomy in infancy. A research work was carried out in the department of Anatomy, Gauhati Medical College. The morphological characteristics of 21 normal human spleens were studied in different age groups and to correlate them functionally. The specimen of spleen varies from newborn to eighty year old cadavers, within stipulated time limit after fulfilling the formalities. The spleens were first washed in normal saline, dried with blotting paper, weight was taken by electronic weighing machine and dimensions are measured by verniar calliper. The dimensions and weight were measured and statistically analysed. The recorded data were then statistically analysed using Student's T-test. P value 0.05 is considered as statistically significant. The data obtained in this study will help in certain medico-legal practices. This study may be used as a pedestal for further sophisticated studies.Keywords
Human Spleen, Length , Breath, Thickness, Weight.Full Text
- A Study on the Size of Pineal Gland in Different Ages
Authors
1 Dept. of Anatomy, Gauhati Medical College, Guwahati-32, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 3, No 2 (2017), Pagination: 49-52Abstract
Introduction: At various times in the history of medicine the precise function of the small discrete pea-like structure we have in the centre of our brains, called the pineal gland (“corpus pineale”), was considered to be a memory valve, a valve controlling circulating vital fluids, the seat of the soul, and the site of a presumed pathology causing certain types of mental illness. In the mid nineteen fifties this confusion began to clear when the pineal gland’s true function was discovered. The gland is a neuroendocrine gland and consists of parenchymal cells, called pinealocytes and neuroglial cells. Melatonin, 5methoxy- N-acetyltryptamin, is a neurohormone of the brain produced by pineal gland. The modern systematic study of the pineal gland began in 1954. There are very few literatures where the size of the pineal gland has been described.
Material and Methods: In the present study 50 numbers of MRI cases done for various purposes, where no pathology of brain was detected were taken in the Radiology department of Gauhati Medical College after obtaining due consent. The length (Anteroposterior diameter) and breadth (Cranio-caudaldiameter) of the pineal gland was recorded. The data recorded was analysed statistically using Student’s T-test. P value d” 0.05 is considered as statistically significant.
Result: The maximum mean length of pineal gland was observed asbe 5.715±0.651 mm in the age group of ‘20 to below 40’ years.
Discussion: The findings of our study has the similar [ty with the observations made by other researchers f this field.
Conclusion: Such a study may be useful in establishing a database which may be useful in correlating the size of the gland with various brain pathology.
Keywords
Neuroendocrine Gland, Antero-Posterior Diameter, Cranio-Caudal Diameter.Full Text