Dental Journal of Advance Studies

Kanu Jain ¹, Monica Mehendiratta ², Deepti Garg Jindal ³, Mohit Bansal ⁴

Affiliations
1 Sudha Rustagi Dental College and Research Institute, Faridabad, Haryana, IN
2 Inderprastha Dental College and Hospital, Ghaziabad, Uttar Pradesh, IN
3 Dept. of Oral and Maxillofacial Pathology, Bhojia Dental College, Distt. Solan, Himachal Pradesh, IN
4 Department of Community Dentistry, Oral Health Sciences Center, PGIMER, Chandigarh, IN

Abstract

To fully understand cellular processes, scientists often examine events at the level of nucleic acids and protein molecules. These studies are complicated by the fact that cells have miniscule amounts of molecules of interest which are too small to be seen. So we require molecular tools to visualize these molecules. Polymerase chain reaction is one such technique widely used in molecular biology and produce quantities that are sufficient to study and visualize. With the advancement in this technique, it has revolutionized the field of research and diagnosis. In this article, we present a review on the principle, basic technique, applications, limitations and recent advances of Polymerase Chain Reaction.

Keywords

Polymerase Chain Reaction, Deoxyribose Nucleic Acid, DNA Polymerase.

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Deepti Garg Jindal ¹, Varun Jindal ², Himanshu Singh ³, Swati Gautam ⁴, Ishita Bhojia ⁴, Arjun Chaudhary ⁵

Affiliations
1 Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Himachal Pradesh, IN
2 Department of Conservative Dentistry & Endodontics, Bhojia Dental College & Hospital, Himachal Pradesh, IN
3 Department of Oral Pathology and Microbiology, M. M. Dental College & Hospital, Haryana, IN
4 Department of Oral Pathology and Microbiology, Bhojia Dental College & Hospital, Himachal Pradesh, IN
5 Bhojia Dental College & Hospital, Himachal Pradesh, IN

Abstract

Hypodontia is the congenital absence of less than six teeth because of agenesis. Congenital absence of tooth (hypodontia) from the dental arch, may occur with any tooth, most commonly being third molars , however, absence of permanent mandibular canine is rare. The absence of teeth may be unilateral or bilateral. There are reports showing unilateral occurrence of permanent mandibular canines but agenesis of bilateral mandibular canines is not well documented in the literature and comprehensive review of literature shows paucity of data pertaining to this anomaly. Here we report one such rare case of congenitally missing mandibular permanent canines bilaterally.

Keywords

Hypodontia,ToothAgenesis, Oligodontia, Permanent, Mandibular, Canines.

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Sonia Joshi ¹, Deepti Garg Jindal ¹, Bhavna Rani ¹, Namita Sepolia ¹

Affiliations
1 Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Himachal Pradesh, IN

Abstract

Oral diseases are among the most common diseases of human kind, yet they receive little attention in many countries with weak health care systems. Despite a high social and economic burden from oral diseases they are considered a neglected area of international health. The purpose of this mini review is to highlight the effects of oral health on general body and vice versa as well as strategies for improving oral health.

Keywords

Diseases, Health, Oral.

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